Duoneb and Januvia drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Duoneb (albuterol sulfate; ipratropium bromide) and Januvia (sitagliptin phosphate). Common drug interactions include injection site haemorrhage among females and cardiac failure congestive among males.
The phase IV clinical study analyzes what interactions people have when they take Duoneb and Januvia. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.
What is Duoneb?
Duoneb has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 8,093 Duoneb users. Check the latest studies of Duoneb.
What is Januvia?
Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.
95 people who take Duoneb and Januvia together, and have interactions are studied.

What are the common drug interactions of Duoneb and Januvia, by gender? *:
female:
- Injection site haemorrhage (bleeding from injection site)
- Perirectal abscess
- Pneumonia
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Urinary tract infection
- Vomiting
- Cardiac arrest
- Cellulitis (infection under the skin)
- Pyrexia (fever)
- Anxiety
male:
- Cardiac failure congestive
- Cough
- Dizziness
- Headache (pain in head)
- Multiple myeloma (cancer of the plasma cells)
- Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
- Oropharyngeal pain
- Refractory anaemia (an anaemia which does not respond to treatment)
- Renal failure (kidney dysfunction)
- Respiratory failure (inadequate gas exchange by the respiratory system)
What are the common drug interactions of Duoneb and Januvia, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Cough
- Panic attack
- Pruritus (severe itching of the skin)
- Throat tightness
30-39:
n/a
40-49:
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Oral mucosal blistering (mouth ulcer)
- Pyrexia (fever)
- Pulmonary embolism (blockage of the main artery of the lung)
50-59:
- Acute respiratory failure
- Anxiety
- Arteriosclerosis (thickening and hardening of arteries)
- Arthralgia (joint pain)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac failure
- Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
- Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
- Corynebacterium infection (infection by corynebacterium (diphtheria))
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
60+:
- Chronic kidney disease
- Dyspnoea (difficult or laboured respiration)
- Death
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Renal tubular necrosis (death of kidney tubules)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Abscess limb (limb infection)
- Acute myocardial infarction (acute heart attack)
- Acute respiratory failure
- Anxiety
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 15.79%
- Type 2 Diabetes: 13 people, 13.68%
- High Blood Cholesterol: 11 people, 11.58%
- Pain: 10 people, 10.53%
- Asthma: 9 people, 9.47%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 8.42%
- Nausea (feeling of having an urge to vomit): 7 people, 7.37%
- High Blood Pressure: 7 people, 7.37%
- Stress And Anxiety: 6 people, 6.32%
- Osteoporosis (bones weak and more likely to break): 6 people, 6.32%
* Approximation only. Some reports may have incomplete information.
Do you take Duoneb and Januvia?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Duoneb and Januvia:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Duoneb:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Januvia:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Duoneb and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Januvia and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Liao KF, Lin CL, Lai SW, Chen WC, "Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan", European journal of internal medicine, 2016 Jan .
- Belice T, Yuce S, Kizilkaya B, Kurt A, Cure E, "Noncardiac pulmonary edema induced by sitagliptin treatment", Journal of family medicine and primary care, 2014 Jan .
- Misgar, R. A., Bhat, J. A., Wani, A. I., & Bashir, M. I., "Sitagliptin induced splenic infarcts", Clinical Diabetology, 2014 Jan .
- Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
- Liao KF, Lin CL, Lai SW, Chen WC, "Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan", European journal of internal medicine, 2016 Jan .
- Belice T, Yuce S, Kizilkaya B, Kurt A, Cure E, "Noncardiac pulmonary edema induced by sitagliptin treatment", Journal of family medicine and primary care, 2014 Jan .
- Misgar, R. A., Bhat, J. A., Wani, A. I., & Bashir, M. I., "Sitagliptin induced splenic infarcts", Clinical Diabetology, 2014 Jan .
- Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide and sitagliptin phosphate (the active ingredients of Duoneb and Januvia, respectively), and Duoneb and Januvia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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