Duoneb and Opdivo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duoneb (albuterol sulfate; ipratropium bromide) and Opdivo (nivolumab). Common drug interactions include malignant neoplasm progression among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Duoneb and Opdivo. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Duoneb?

Duoneb has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 8,093 Duoneb users. Check the latest studies of Duoneb.

What is Opdivo?

Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.

On Jul, 27, 2026

23 people who take Duoneb and Opdivo together, and have interactions are studied.

What are the common drug interactions of Duoneb and Opdivo, by gender? *:

female:

Malignant neoplasm progression (cancer tumour came back)
Anaemia (lack of blood)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Constipation
Mucosal inflammation (infection of mucous membrane)
Nausea (feeling of having an urge to vomit)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Vomiting
Nephrolithiasis (calculi in the kidneys)
Respiratory failure (inadequate gas exchange by the respiratory system)

male:

Death
Malignant neoplasm progression (cancer tumour came back)
Neuropathy peripheral (surface nerve damage)
Pericardial effusion (fluid around the heart)
Peripheral swelling
Pneumonia
Pulmonary oedema (fluid accumulation in the lungs)
Thermal burn (burn by heat)
Vomiting
Weight decreased

What are the common drug interactions of Duoneb and Opdivo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Acute respiratory failure
Anaemia (lack of blood)
Appetite disorder (abnormal eating habits)
Blood pressure systolic decreased
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Malignant neoplasm progression (cancer tumour came back)
Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)

40-49:

Renal failure (kidney dysfunction)

50-59:

n/a

60+:

Death
Malignant neoplasm progression (cancer tumour came back)
Acute respiratory failure
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bladder spasm
Cancer pain
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Delirium (wild excitement)

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 7 people, 30.43%
Pain: 3 people, 13.04%
Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 2 people, 8.70%
Nausea And Vomiting: 2 people, 8.70%
Nausea (feeling of having an urge to vomit): 2 people, 8.70%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 8.70%
Lung Carcinoma Cell Type Unspecified Stage Iv (the lung cancer has spread to other organs of the body, such as the other lung, brain, or liver): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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