Duphalac and Ezetimibe drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duphalac (lactulose) and Ezetimibe (ezetimibe). Common drug interactions include bradycardia among females and palmar-plantar erythrodysaesthesia syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Duphalac and Ezetimibe. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Duphalac?

Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.

What is Ezetimibe?

Ezetimibe has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 30,849 Ezetimibe users. Check the latest studies of Ezetimibe.

On Aug, 09, 2026

36 people who take Duphalac and Ezetimibe together, and have interactions are studied.

Duphalac and Ezetimibe drug interactions.

What are the common drug interactions of Duphalac and Ezetimibe, by gender? *:

female:

Bradycardia (abnormally slow heart action)
Coma (state of unconsciousness lasting more than six hours)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Atrioventricular block complete (heart block complete)
Vomiting
Abdominal wall haematoma (abdominal wall blood clotting)
Anaemia (lack of blood)
Diabetes mellitus inadequate control
Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)

male:

Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Abdominal distension
Hypertension (high blood pressure)
Oedema peripheral (superficial swelling)
Electrocardiogram qt prolonged
Acquired haemophilia (bleeding disorder disease)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Febrile neutropenia (fever with reduced white blood cells)

What are the common drug interactions of Duphalac and Ezetimibe, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Diabetes mellitus inadequate control

60+:

Bradycardia (abnormally slow heart action)
Coma (state of unconsciousness lasting more than six hours)
Varicose ulceration
Diarrhoea
Dizziness
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Atrioventricular block complete (heart block complete)
Vomiting
Electrocardiogram qt prolonged

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 22.22%
Renal Cell Carcinoma (a kidney cancer): 6 people, 16.67%
Depression: 6 people, 16.67%
Renal Cancer Metastatic (cancer of kidney spreads to other part): 5 people, 13.89%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 11.11%
Cardiac Failure Chronic: 3 people, 8.33%
Dyslipidaemia (abnormal amount of lipids): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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