Duphalac and Sporanox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duphalac (lactulose) and Sporanox (itraconazole). Common drug interactions include hypokalaemia among females and atrial flutter among males.

The phase IV clinical study analyzes what interactions people have when they take Duphalac and Sporanox. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Duphalac?

Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.

What is Sporanox?

Sporanox has active ingredients of itraconazole. It is often used in fungal infection. eHealthMe is studying from 6,137 Sporanox users. Check the latest studies of Sporanox.

On Jul, 28, 2026

16 people who take Duphalac and Sporanox together, and have interactions are studied.

Duphalac and Sporanox drug interactions.

What are the common drug interactions of Duphalac and Sporanox, by gender? *:

female:

Hypokalaemia (low potassium)
Syncope (loss of consciousness with an inability to maintain postural tone)
Arrhythmia (irregular heartbeat)
Blood pressure fluctuation

male:

Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Cardiac arrest
Lung transplant
Anal haemorrhage
Hiv antibody positive
Meningitis viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Confusional state
Erythema (redness of the skin)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Oral candidiasis (fungal infection of mouth)

What are the common drug interactions of Duphalac and Sporanox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anal haemorrhage
Hiv antibody positive
Meningitis viral (viral inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Ammonia increased
Confusional state
Fatigue (feeling of tiredness)
Lung transplant rejection (failure of lung transplant)
Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)

50-59:

Hypokalaemia (low potassium)
Syncope (loss of consciousness with an inability to maintain postural tone)
Arrhythmia (irregular heartbeat)
Blood pressure fluctuation
Diabetes insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function)
Infection
Polydipsia (excessive thirst)
Polyuria (production of too much dilute urine)
Staphylococcal infection (an infection with staphylococcus bacteria)

60+:

Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Cardiac arrest
Lung transplant
Erythema (redness of the skin)
Oral candidiasis (fungal infection of mouth)
Pruritus (severe itching of the skin)
Pulmonary embolism (blockage of the main artery of the lung)
Cardiac failure congestive
Confusional state
Decreased appetite

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 18.75%
Respiratory Depression (respiration has a rate below 12 breaths): 3 people, 18.75%
Pain: 2 people, 12.50%
Oral Candidiasis (fungal infection of mouth): 2 people, 12.50%
Gastric Cancer (stomach cancer): 2 people, 12.50%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 6.25%
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 1 person, 6.25%
Cough: 1 person, 6.25%
Coughing Up Blood: 1 person, 6.25%
Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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