Duphalac and Valproic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duphalac (lactulose) and Valproic acid (valproic acid). Common drug interactions include choking among females and lymphocyte count increased among males.

The phase IV clinical study analyzes what interactions people have when they take Duphalac and Valproic acid. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Duphalac?

Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.

What is Valproic acid?

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.

On Jul, 21, 2026

14 people who take Duphalac and Valproic acid together, and have interactions are studied.

Duphalac and Valproic acid drug interactions.

What are the common drug interactions of Duphalac and Valproic Acid, by gender? *:

female:

Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Infection
Pleural effusion (water on the lungs)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Weight increased
Granulocytopenia (lack of granulocyte)
Abscess neck (neck abscesses)
Anasarca (general swelling, or massive oedema)
Blood triglycerides increased

male:

Lymphocyte count increased
Platelet count decreased
White blood cell count increased
Anisocytosis (patient's red blood cells are of unequal size)
Ataxia (loss of full control of bodily movements)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Pancreatitis acute (sudden inflammation of pancreas)

What are the common drug interactions of Duphalac and Valproic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Granulocytopenia (lack of granulocyte)
Pancreatitis acute (sudden inflammation of pancreas)

40-49:

n/a

50-59:

White blood cell count increased
Anisocytosis (patient's red blood cells are of unequal size)
Pneumonia
Atelectasis (partial or complete collapse of the lung)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Infection
Pleural effusion (water on the lungs)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Abscess neck (neck abscesses)

60+:

Coma (state of unconsciousness lasting more than six hours)
Depressed level of consciousness
Hyperammonaemia
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Oral intake reduced
Pyrexia (fever)
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

Diabetes: 6 people, 42.86%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 35.71%
Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 4 people, 28.57%
High Blood Pressure: 4 people, 28.57%
Psychotic Disorder: 2 people, 14.29%
Insomnia (sleeplessness): 2 people, 14.29%
Stress And Anxiety: 1 person, 7.14%
Sleep Disorder: 1 person, 7.14%
Pyramidal Tract Syndrome (disorder characterized by dysfunction of the corticospinal (pyramidal) tracts of the spinal cord): 1 person, 7.14%
Osteoporosis (bones weak and more likely to break): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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