Duragesic-100 and Septra ds drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duragesic-100 (fentanyl) and Septra ds (sulfamethoxazole; trimethoprim). Common drug interactions include anxiety among females.

The phase IV clinical study analyzes what interactions people have when they take Duragesic-100 and Septra ds. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Duragesic-100?

Duragesic-100 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 19,509 Duragesic-100 users. Check the latest studies of Duragesic-100.

What is Septra ds?

Septra ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 2,349 Septra ds users. Check the latest studies of Septra ds.

On Jul, 11, 2026

18 people who take Duragesic-100 and Septra ds together, and have interactions are studied.

Duragesic-100 and Septra ds drug interactions.

What are the common drug interactions of Duragesic-100 and Septra Ds, by gender? *:

female:

Anxiety
Renal failure (kidney dysfunction)
Hypokalaemia (low potassium)
Injury
Multiple myeloma (cancer of the plasma cells)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nausea (feeling of having an urge to vomit)
Nocturia (the need to get up in the night to urinate)
Oesophageal candidiasis (fungal infection of oesophagus)
Oesophageal pain

male:

n/a

What are the common drug interactions of Duragesic-100 and Septra Ds, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anaemia (lack of blood)
Anxiety
Asthma
Bone pain
Chest pain
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Compression fracture (fracture due to pressure caused by injury)
Headache (pain in head)
Hypokalaemia (low potassium)
Injury

40-49:

Blood alkaline phosphatase increased
Blood creatinine increased
Chest pain
Compression fracture (fracture due to pressure caused by injury)
Constipation
Dyspepsia (indigestion)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)

50-59:

n/a

60+:

Anxiety
Confusional state
Hypotension (abnormally low blood pressure)
Lipase increased
Loss of consciousness
Renal failure acute (rapid kidney dysfunction)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Vascular dementia (vascular dementia is a general term describing problems with reasoning, planning, judgment, memory and other thought)
Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
Atherosclerosis (disorder of the arteries)

What are the existing conditions these people have? *

Sleep Disorder: 1 person, 5.56%
Seasonal Allergy (allergic condition due to certain season): 1 person, 5.56%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 5.56%
Nausea (feeling of having an urge to vomit): 1 person, 5.56%
Itching: 1 person, 5.56%
Insomnia (sleeplessness): 1 person, 5.56%
Impaired Gastric Emptying: 1 person, 5.56%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.56%
Breakthrough Pain: 1 person, 5.56%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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