Duragesic-50 and Bactrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duragesic-50 (fentanyl) and Bactrim (sulfamethoxazole; trimethoprim). Common drug interactions include antinuclear antibody positive among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Duragesic-50 and Bactrim. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Duragesic-50?

Duragesic-50 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 733 Duragesic-50 users. Check the latest studies of Duragesic-50.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

On Jul, 25, 2026

12 people who take Duragesic-50 and Bactrim together, and have interactions are studied.

Duragesic-50 and Bactrim drug interactions.

What are the common drug interactions of Duragesic-50 and Bactrim, by gender? *:

female:

Antinuclear antibody positive
Anxiety
Arthralgia (joint pain)
Arthropathy
Asthma
Back pain
Bedridden
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone marrow failure
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

Anxiety
Depression
Intervertebral disc degeneration (spinal disc degeneration)
Neoplasm malignant (cancer tumour)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Rash pruritic (redness with itching)
Arthralgia (joint pain)
Deformity (disfigurement)
Discomfort
Dysuria (painful or difficult urination)

What are the common drug interactions of Duragesic-50 and Bactrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abscess jaw (tooth abscess or root abscess)
Anxiety
Ataxia (loss of full control of bodily movements)
Blood alkaline phosphatase increased
Blood immunoglobulin g increased
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone swelling
Cardiac disorder
Cardiomegaly (increased size of heart than normal)

40-49:

Anxiety
Diarrhoea
Asthenia (weakness)
Back pain
Confusional state
Depression
Fall
Gait disturbance
Neuropathy peripheral (surface nerve damage)
Osteonecrosis of jaw (death of bone of jaw)

50-59:

Epicondylitis (tennis elbow)
Fat tissue increased
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Foot fracture
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypoaesthesia (reduced sense of touch or sensation)
Intervertebral disc space narrowing (spinal disc space narrowing)
Joint sprain (an injury to joint surrounding flexible fibres)
Mastication disorder (disease of chewing food)
Mouth ulceration (mouth ulcers)

60+:

Anaemia (lack of blood)
Anxiety
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest pain
Conjunctival haemorrhage (bleeding underneath the conjunctiva)
Dyspnoea (difficult or laboured respiration)
Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
Fatigue (feeling of tiredness)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hypercalcaemia (elevated calcium (ca+) level in the blood)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 50.00%
Stress And Anxiety: 2 people, 16.67%
Depression: 2 people, 16.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 16.67%
Weight Decreased: 1 person, 8.33%
Initial Insomnia (feeling of inadequate or poor-quality sleep): 1 person, 8.33%
Birth Control: 1 person, 8.33%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 8.33%
Constipation: 1 person, 8.33%
Gastritis (inflammation of stomach): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Duragesic-50 and Bactrim?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously