Duragesic-50 and Loraz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duragesic-50 (fentanyl) and Loraz (lorazepam). Common drug interactions include pain in extremity among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Duragesic-50 and Loraz. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Duragesic-50?

Duragesic-50 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 733 Duragesic-50 users. Check the latest studies of Duragesic-50.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.

On Jul, 20, 2026

18 people who take Duragesic-50 and Loraz together, and have interactions are studied.

Duragesic-50 and Loraz drug interactions.

What are the common drug interactions of Duragesic-50 and Loraz, by gender? *:

female:

Pain in extremity
Anaemia (lack of blood)
Calcification of muscle (calcium accumulation in muscle)
Decreased appetite
Depressed level of consciousness
Emotional distress
Fatigue (feeling of tiredness)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Gait disturbance
Haematocrit decreased

male:

Abdominal pain
Anaemia (lack of blood)
Osteonecrosis of jaw (death of bone of jaw)
Back pain
Adrenal neoplasm (abnormal growth of adrenal gland)
Biliary cyst
Bladder hypertrophy (bladder overgrowth- increase in cell size)
Blood testosterone decreased
Blood urine present
Bone density decreased

What are the common drug interactions of Duragesic-50 and Loraz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Arthralgia (joint pain)
Back pain
Dizziness
Gastritis (inflammation of stomach)
Joint effusion (presence of extra fluid in joint covering)
Laceration (tearing of soft body tissue)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Nausea (feeling of having an urge to vomit)
Oropharyngeal pain

40-49:

Biliary cyst
Bladder hypertrophy (bladder overgrowth- increase in cell size)
Blood testosterone decreased
Bone density decreased
Breast tenderness
Calculus bladder (bladder stone)
Calculus ureteric (stone in ureter)
Cardiomegaly (increased size of heart than normal)
Chills (felling of cold)
Colitis (inflammation of colon)

50-59:

Biliary cyst
Bladder hypertrophy (bladder overgrowth- increase in cell size)
Blood testosterone decreased
Blood urine present
Bone density decreased
Bone disorder
Bone pain
Breast tenderness
Calculus bladder (bladder stone)
Chills (felling of cold)

60+:

Abdominal discomfort
Brain neoplasm (tumour of brain)
Death
Diarrhoea
Flatulence (flatus expelled through the anus)
Second primary malignancy (after getting cure a cancer, a new cancer development)

What are the existing conditions these people have? *

Back Pain: 3 people, 16.67%
Prostate Cancer: 3 people, 16.67%
Osteoporosis (bones weak and more likely to break): 3 people, 16.67%
Type 2 Diabetes: 2 people, 11.11%
Bone Pain: 2 people, 11.11%
Depression: 2 people, 11.11%
Initial Insomnia (feeling of inadequate or poor-quality sleep): 1 person, 5.56%
Birth Control: 1 person, 5.56%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 5.56%
Gastritis (inflammation of stomach): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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