Duragesic and Apixaban drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Duragesic (fentanyl) and Apixaban (apixaban). Common drug interactions include disease progression among females and acute respiratory failure among males.
The phase IV clinical study analyzes what interactions people have when they take Duragesic and Apixaban. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Duragesic?
Duragesic has active ingredients of fentanyl. eHealthMe is studying from 66,597 Duragesic users. Check the latest studies of Duragesic.
What is Apixaban?
Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.
11 people who take Duragesic and Apixaban together, and have interactions are studied.

What are the common drug interactions of Duragesic and Apixaban, by gender? *:
female:
- Disease progression
- Death
- Hypersensitivity
- Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
- Malignant neoplasm progression (cancer tumour came back)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Pyrexia (fever)
male:
- Acute respiratory failure
- Aspartate aminotransferase increased
- Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
- Metastases to spine (cancer spreads to spine)
- Oedema peripheral (superficial swelling)
- Pelvic pain
- Pulmonary embolism (blockage of the main artery of the lung)
- Pyrexia (fever)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased)
What are the common drug interactions of Duragesic and Apixaban, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Disease progression
- Hypercapnia (too much smoke)
- Hypoxia (low oxygen in tissues)
- Iron deficiency anaemia
- Leukopenia (less number of white blood cells in blood)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
- Metastases to spine (cancer spreads to spine)
- Oedema peripheral (superficial swelling)
- Pelvic pain
50-59:
- Pyrexia (fever)
60+:
- Death
- Disease progression
- Hypersensitivity
- Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
- Malignant neoplasm progression (cancer tumour came back)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
What are the existing conditions these people have? *
- Pain: 7 people, 63.64%
- Constipation: 5 people, 45.45%
- Nausea (feeling of having an urge to vomit): 3 people, 27.27%
- Stress And Anxiety: 3 people, 27.27%
- Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 27.27%
- Multiple Myeloma (cancer of the plasma cells): 3 people, 27.27%
- Nausea And Vomiting: 2 people, 18.18%
- Dyspnea (difficult or laboured breathing): 2 people, 18.18%
- High Blood Pressure: 2 people, 18.18%
- Hypersensitivity: 2 people, 18.18%
* Approximation only. Some reports may have incomplete information.
Do you take Duragesic and Apixaban?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Duragesic and Apixaban:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Duragesic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Apixaban:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Duragesic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Apixaban and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on fentanyl and apixaban (the active ingredients of Duragesic and Apixaban, respectively), and Duragesic and Apixaban (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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