Duragesic and Cefazolin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duragesic (fentanyl) and Cefazolin (cefazolin sodium). Common drug interactions include intervertebral disc protrusion among females and drug toxicity among males.

The phase IV clinical study analyzes what interactions people have when they take Duragesic and Cefazolin. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Duragesic?

Duragesic has active ingredients of fentanyl. eHealthMe is studying from 66,597 Duragesic users. Check the latest studies of Duragesic.

What is Cefazolin?

Cefazolin has active ingredients of cefazolin sodium. It is often used in infection. eHealthMe is studying from 15,157 Cefazolin users. Check the latest studies of Cefazolin.

On Jul, 12, 2026

75 people who take Duragesic and Cefazolin together, and have interactions are studied.

Duragesic and Cefazolin drug interactions.

What are the common drug interactions of Duragesic and Cefazolin, by gender? *:

female:

Intervertebral disc protrusion (spinal disc protrusion)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)
Spinal osteoarthritis (joint cartilage loss in spine)
Urinary tract infection
Asthma
Osteomyelitis (infection of bone)
Arthropathy
Diarrhoea
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

male:

Drug toxicity
Hypertensive heart disease
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Deafness
Death
Foot fracture
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)
Pain in extremity

What are the common drug interactions of Duragesic and Cefazolin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Acute pulmonary oedema (sudden deposit of fluid in the lung))
Drug toxicity
Back pain
Pain in extremity
Abdominal distension
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Overdose
Unresponsive to stimuli
Accidental death
Application site pain

20-29:

n/a

30-39:

Abdominal pain
Anaemia (lack of blood)
Anxiety
Appendicitis (inflammation of the appendix)
Arthropathy
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Bone pain
Breast cancer recurrent
Confusional state
Constipation

40-49:

Abnormal behaviour
Aggression
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety disorder
Device occlusion
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dyspnoea (difficult or laboured respiration)
Eating disorder
Hospitalisation

50-59:

Osteonecrosis of jaw (death of bone of jaw)
Pain in extremity
Sinusitis (inflammation of sinus)
Swelling
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Mastication disorder (disease of chewing food)
Mouth ulceration (mouth ulcers)
Oral candidiasis (fungal infection of mouth)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Abscess oral (abscess in the mouth)

60+:

Renal failure (kidney dysfunction)
Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diarrhoea
Emotional distress
Fear
Multi-organ failure (multisystem organ failure)
Pain
Stress
Back pain

What are the existing conditions these people have? *

Pain: 23 people, 30.67%
Multiple Myeloma (cancer of the plasma cells): 16 people, 21.33%
High Blood Pressure: 15 people, 20.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 14 people, 18.67%
Metastases To Bone (cancer spreads to bone): 13 people, 17.33%
Breakthrough Pain: 13 people, 17.33%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 13 people, 17.33%
Bacterial Infection: 13 people, 17.33%
Acid Fast Bacilli Infection (mycobacterium tuberculosis infection-hiv patient): 13 people, 17.33%
Procedural Pain: 12 people, 16.00%

* Approximation only. Some reports may have incomplete information.

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