Duragesic and Pradaxa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Duragesic (fentanyl) and Pradaxa (dabigatran etexilate mesylate). Common drug interactions include neuralgia among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Duragesic and Pradaxa. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Duragesic?

Duragesic has active ingredients of fentanyl. eHealthMe is studying from 66,597 Duragesic users. Check the latest studies of Duragesic.

What is Pradaxa?

Pradaxa has active ingredients of dabigatran etexilate mesylate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 86,906 Pradaxa users. Check the latest studies of Pradaxa.

On Jul, 12, 2026

59 people who take Duragesic and Pradaxa together, and have interactions are studied.

Duragesic and Pradaxa drug interactions.

What are the common drug interactions of Duragesic and Pradaxa, by gender? *:

female:

Neuralgia (pain in one or more nerves)
Pain
Tremor (trembling or shaking movements in one or more parts of your body)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Anaemia (lack of blood)
Coronary artery bypass
Drug effect decreased
Haemorrhage (bleeding)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Fall
Renal failure (kidney dysfunction)
Weight decreased
Anaemia (lack of blood)
Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
Pulmonary haematoma (collection of blood within the tissue of the lung)
Rib fracture
Scapula fracture (a fracture of the scapula, the shoulder blade)
Spinal compression fracture (fracture due to spinal compression on bone)

What are the common drug interactions of Duragesic and Pradaxa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemorrhagic anaemia (anaemia due to excessive bleeding)

40-49:

Anaemia postoperative
Blood glucose increased
Cellulitis (infection under the skin)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cholecystitis acute (rapid infection of gallbladder)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Fasciitis (infection of muscle surrounding tissue)
Gastric haemorrhage (bleeding stomach)
Gastroenteritis (inflammation of stomach and intestine)
Haematochezia (passage of stools containing blood)

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Epistaxis (bleed from the nose)
Fall
Haemorrhage (bleeding)
Pain in extremity

60+:

Drug ineffective
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Anaemia (lack of blood)
Coronary artery bypass
Renal failure (kidney dysfunction)
Coagulopathy (blood's ability to clot is impaired)
Fall
Back pain
Decreased appetite

What are the existing conditions these people have? *

Pain: 15 people, 25.42%
High Blood Cholesterol: 12 people, 20.34%
Depression: 7 people, 11.86%
High Blood Pressure: 7 people, 11.86%
Nausea (feeling of having an urge to vomit): 6 people, 10.17%
Cardiac Failure: 6 people, 10.17%
Glaucoma (increased fluid pressure in the eye with vision loss): 6 people, 10.17%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 6 people, 10.17%
Asthma: 6 people, 10.17%
Muscle Spasms (muscle contraction): 5 people, 8.47%

* Approximation only. Some reports may have incomplete information.

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