Durezol and Rituxan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Durezol (difluprednate) and Rituxan (rituximab). Common drug interactions include depression among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Durezol and Rituxan. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Durezol?

Durezol has active ingredients of difluprednate. It is often used in uveitis. eHealthMe is studying from 3,441 Durezol users. Check the latest studies of Durezol.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.



On Aug, 02, 2026

22 people who take Durezol and Rituxan together, and have interactions are studied.

Durezol and Rituxan drug interactions.

What are the common drug interactions of Durezol and Rituxan, by gender? *:

female:

  1. Depression
  2. Nausea (feeling of having an urge to vomit)
  3. Eye disorder
  4. Acne (skin problems that cause pimples)
  5. Aphthous ulcer (mouth ulcer)
  6. Cataract (clouding of the lens inside the eye)
  7. Heart rate increased
  8. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  9. Mouth ulceration (mouth ulcers)
  10. Oral pain

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Pleural effusion (water on the lungs)
  3. Death
  4. Cataract (clouding of the lens inside the eye)
  5. Diarrhoea
  6. Hospitalisation

What are the common drug interactions of Durezol and Rituxan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Acne (skin problems that cause pimples)
  2. Aphthous ulcer (mouth ulcer)
  3. Cataract (clouding of the lens inside the eye)
  4. Depression
  5. Heart rate increased
  6. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  7. Oral pain

30-39:

  1. Abdominal pain upper
  2. Chest discomfort
  3. Decreased appetite
  4. Depression
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Migraine (headache)
  7. Mood swings (an extreme or rapid change in mood)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Nausea (feeling of having an urge to vomit)
  10. Pneumonia

40-49:

n/a

50-59:

  1. Headache (pain in head)
  2. Muscle tightness
  3. Nausea (feeling of having an urge to vomit)
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Skin discolouration (change of skin colour)
  6. Skin infection
  7. Arthropod sting (arthropod bite)
  8. Drug hypersensitivity
  9. Fall
  10. Head injury

60+:

  1. Death
  2. Diarrhoea

What are the existing conditions these people have? *

  1. Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 6 people, 27.27%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 18.18%
  3. Pemphigoid (tense blisters on the skin): 3 people, 13.64%
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 13.64%
  5. Iridocyclitis (inflammation of the iris and ciliary body of the eye): 3 people, 13.64%
  6. Stress And Anxiety: 2 people, 9.09%
  7. Ocular Pemphigoid (inflammatory autoimmune disorder characterized by blistering lesions that affect mucous membrane covering of eye): 2 people, 9.09%
  8. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 9.09%
  9. Abdominal Discomfort: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Durezol and Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Durezol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Durezol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rituxan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on difluprednate and rituximab (the active ingredients of Durezol and Rituxan, respectively), and Durezol and Rituxan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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