Dyazide and Invokamet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dyazide (hydrochlorothiazide; triamterene) and Invokamet (canagliflozin; metformin hydrochloride). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Dyazide and Invokamet. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Dyazide?

Dyazide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 11,506 Dyazide users. Check the latest studies of Dyazide.

What is Invokamet?

Invokamet has active ingredients of canagliflozin; metformin hydrochloride. eHealthMe is studying from 1,965 Invokamet users. Check the latest studies of Invokamet.

On Jul, 18, 2026

15 people who take Dyazide and Invokamet together, and have interactions are studied.

Dyazide and Invokamet drug interactions.

What are the common drug interactions of Dyazide and Invokamet, by gender? *:

female:

Pain
Nephrolithiasis (calculi in the kidneys)
Spinal fusion surgery
Asthenia (weakness)
Asthma
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Gait disturbance
Gastrointestinal infection (infection of stomach and intestine)
Hypoaesthesia (reduced sense of touch or sensation)

male:

n/a

What are the common drug interactions of Dyazide and Invokamet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cystitis (inflammation of the wall of the bladder)
Hospitalisation
Memory impairment
Spinal fusion surgery
Asthma
Diplopia (double vision)
Hysterectomy
Pain
Poor quality sleep
Retinal vascular disorder (a range of eye diseases that affect the blood vessels in the eye)

50-59:

Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Upper respiratory tract infection
Diarrhoea
Gait disturbance
Gastrointestinal infection (infection of stomach and intestine)
Hypoaesthesia (reduced sense of touch or sensation)
Nasopharyngitis (inflammation of the nasopharynx)
Seasonal allergy (allergic condition due to certain season)
Sleep disorder

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 93.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 66.67%
Drowsiness: 2 people, 13.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.67%
Insomnia (sleeplessness): 1 person, 6.67%
Gait Disturbance: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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