Dyazide and Senna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dyazide (hydrochlorothiazide; triamterene) and Senna (senna). Common drug interactions include ascites among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Dyazide and Senna. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Dyazide?

Dyazide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 11,506 Dyazide users. Check the latest studies of Dyazide.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

On Jul, 15, 2026

53 people who take Dyazide and Senna together, and have interactions are studied.

What are the common drug interactions of Dyazide and Senna, by gender? *:

female:

Ascites (accumulation of fluid in the abdominal cavity)
Balance disorder
Body temperature increased
Bone density decreased
Bone loss
Cardiac disorder
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Deafness unilateral
Pleural effusion (water on the lungs)
Fluid overload (too much fluid in the blood)

male:

Abdominal discomfort
Vision blurred
Full blood count decreased
Glaucoma (increased fluid pressure in the eye with vision loss)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypophagia (reduced food intake)
Impaired driving ability
Inappropriate antidiuretic hormone secretion
Lung neoplasm malignant (cancer tumour of lung)
Mesenteric artery stenosis (narrowing of the arteries supplying blood to the intestines)

What are the common drug interactions of Dyazide and Senna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Confusional state
Deafness unilateral
Diarrhoea
Dizziness
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Night blindness (inability to see in night as day)

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Female genital tract fistula (passage in genital tract of female)
Headache (pain in head)
Arthralgia (joint pain)
Back pain
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)

50-59:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Platelet count decreased
Pulmonary oedema (fluid accumulation in the lungs)
Pyrexia (fever)
Renal failure chronic (long lasting kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Rib fracture
Staphylococcal bacteraemia (a bacterial infection of blood)

60+:

Pleural effusion (water on the lungs)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Depression
Fibrin d dimer increased
Fluid overload (too much fluid in the blood)
Foaming at mouth (excess saliva secretion)
Haemoglobin decreased
Hepatic cyst
Hypochloraemia (electrolyte disturbance in which there is an abnormally low level of the chloride ion in the blood)
Hypoglycaemic coma (coma due to deficiency of glucose in the bloodstream)

What are the existing conditions these people have? *

Pain: 13 people, 24.53%
Depression: 8 people, 15.09%
Stress And Anxiety: 8 people, 15.09%
Restless Leg Syndrome (a powerful urge to move your legs): 8 people, 15.09%
Nausea (feeling of having an urge to vomit): 8 people, 15.09%
Lung Cancer - Non-Small Cell (lung cancer): 7 people, 13.21%
High Blood Cholesterol: 6 people, 11.32%
Colon Cancer: 6 people, 11.32%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 9.43%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 7.55%

* Approximation only. Some reports may have incomplete information.

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