Dynacirc and Duragesic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dynacirc (isradipine) and Duragesic (fentanyl). Common drug interactions include dysuria among females and aspergillosis among males.

The phase IV clinical study analyzes what interactions people have when they take Dynacirc and Duragesic. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Dynacirc?

Dynacirc has active ingredients of isradipine. eHealthMe is studying from 975 Dynacirc users. Check the latest studies of Dynacirc.

What is Duragesic?

Duragesic has active ingredients of fentanyl. eHealthMe is studying from 66,597 Duragesic users. Check the latest studies of Duragesic.



On Jul, 18, 2026

21 people who take Dynacirc and Duragesic together, and have interactions are studied.

Dynacirc and Duragesic drug interactions.

What are the common drug interactions of Dynacirc and Duragesic, by gender? *:

female:

  1. Dysuria (painful or difficult urination)
  2. Fatigue (feeling of tiredness)
  3. Metastases to lung (cancer spreads to lung)
  4. Myalgia (muscle pain)
  5. Oedema peripheral (superficial swelling)
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Abdominal discomfort
  8. Dry mouth
  9. Dyspnoea (difficult or laboured respiration)
  10. Stomatitis (inflammation of mucous membrane of mouth)

male:

  1. Aspergillosis (an infection caused by a fungus called aspergillus)
  2. Back pain
  3. Loss of consciousness
  4. Nausea (feeling of having an urge to vomit)
  5. Renal failure acute (rapid kidney dysfunction)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Syncope (loss of consciousness with an inability to maintain postural tone)
  8. Unresponsive to stimuli
  9. Waldenstrom's macroglobulinaemia (cancer affects small lymphocytes (white blood cells))
  10. Confusional state

What are the common drug interactions of Dynacirc and Duragesic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Blood alkaline phosphatase increased
  4. Blood bilirubin increased
  5. Gastric cancer (stomach cancer)
  6. Hypertension (high blood pressure)
  7. Linitis plastica

60+:

  1. Dry mouth
  2. Dyspnoea (difficult or laboured respiration)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Impaired healing
  5. Inflammation
  6. Lip ulceration (ulcer of lip)
  7. Mouth ulceration (mouth ulcers)
  8. Osteomyelitis (infection of bone)
  9. Osteosclerosis (an elevation in bone density)
  10. Pain in jaw

What are the existing conditions these people have? *

  1. Pain: 15 people, 71.43%
  2. Metastases To Bone (cancer spreads to bone): 13 people, 61.90%
  3. Breast Cancer: 8 people, 38.10%

* Approximation only. Some reports may have incomplete information.

Do you take Dynacirc and Duragesic?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dynacirc and Duragesic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dynacirc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Duragesic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dynacirc and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duragesic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on isradipine and fentanyl (the active ingredients of Dynacirc and Duragesic, respectively), and Dynacirc and Duragesic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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