Econazole nitrate and Hydroxyzine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Econazole nitrate (econazole nitrate) and Hydroxyzine (hydroxyzine hydrochloride). Common drug interactions include parosmia among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Econazole nitrate and Hydroxyzine. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Econazole nitrate?

Econazole nitrate has active ingredients of econazole nitrate. It is often used in athlete's foot. eHealthMe is studying from 1,264 Econazole nitrate users. Check the latest studies of Econazole nitrate.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.



On Jul, 07, 2026

36 people who take Econazole nitrate and Hydroxyzine together, and have interactions are studied.

Econazole nitrate and Hydroxyzine drug interactions.

What are the common drug interactions of Econazole Nitrate and Hydroxyzine, by gender? *:

female:

  1. Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
  2. Peripheral swelling
  3. Polyp
  4. Precancerous cells present
  5. Pyrexia (fever)
  6. Rash
  7. Renal injury (kidney injury)
  8. Renal tubular necrosis (death of kidney tubules)
  9. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  10. Tension headache

male:

  1. Emotional distress
  2. Chronic kidney disease
  3. Multiple injuries
  4. Dehydration (dryness resulting from the removal of water)
  5. Diarrhoea
  6. Abscess limb (limb infection)
  7. Cellulitis (infection under the skin)
  8. Cellulitis of male external genital organ (infection of male genitals soft tissue)
  9. Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
  10. Gangrene (body tissue dies)

What are the common drug interactions of Econazole Nitrate and Hydroxyzine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Body tinea (ringworm of the body)
  2. Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
  3. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  4. Eosinophil count increased
  5. Erythema (redness of the skin)
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  7. Migraine with aura (headache with vision weakness)
  8. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  9. Nausea (feeling of having an urge to vomit)
  10. Neck pain

50-59:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Chest pain
  5. Colitis ulcerative (inflammation of colon with ulcer)
  6. Constipation
  7. Diarrhoea
  8. Drug ineffective
  9. Eructation (release of gas from the digestive tract)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

  1. Asthenia (weakness)
  2. Dehydration (dryness resulting from the removal of water)
  3. Back pain
  4. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  5. Constipation
  6. Deafness neurosensory
  7. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  8. Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 25.00%
  2. Hiv Infection: 8 people, 22.22%
  3. High Blood Pressure: 6 people, 16.67%
  4. Diabetes: 5 people, 13.89%
  5. High Blood Cholesterol: 5 people, 13.89%
  6. Cardiac Disorder: 4 people, 11.11%
  7. Infection: 4 people, 11.11%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 11.11%
  9. Pain: 4 people, 11.11%
  10. Neuralgia (pain in one or more nerves): 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Econazole nitrate and Hydroxyzine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Econazole nitrate and Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Econazole nitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Econazole nitrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyzine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on econazole nitrate and hydroxyzine hydrochloride (the active ingredients of Econazole nitrate and Hydroxyzine, respectively), and Econazole nitrate and Hydroxyzine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: