Edoxaban and Eplerenone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Edoxaban (edoxaban) and Eplerenone (eplerenone). Common drug interactions include atrial fibrillation among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Edoxaban and Eplerenone. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Edoxaban?

Edoxaban has active ingredients of edoxaban. eHealthMe is studying from 1,783 Edoxaban users. Check the latest studies of Edoxaban.

What is Eplerenone?

Eplerenone has active ingredients of eplerenone. It is often used in high blood pressure. eHealthMe is studying from 9,979 Eplerenone users. Check the latest studies of Eplerenone.

On Jul, 09, 2026

74 people who take Edoxaban and Eplerenone together, and have interactions are studied.

Edoxaban and Eplerenone drug interactions.

What are the common drug interactions of Edoxaban and Eplerenone, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hyperkalaemia (damage to or disease of the kidney)
Arrhythmia (irregular heartbeat)
Anaemia (lack of blood)
Cardiac disorder
Chest pain
Dizziness
Electrocardiogram st segment elevation
General physical health deterioration (weak health status)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Colorectal cancer (colon cancer or bowel cancer)
Dysuria (painful or difficult urination)
Penile pain
Urinary tract obstruction
Vomiting
Benign prostatic hyperplasia (benign enlargement of the prostate)
Dyspnoea (difficult or laboured respiration)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)

What are the common drug interactions of Edoxaban and Eplerenone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Dysuria (painful or difficult urination)
Penile pain
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Urinary tract obstruction
Vomiting
Benign prostatic hyperplasia (benign enlargement of the prostate)
Dyspnoea (difficult or laboured respiration)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 28 people, 37.84%
Cardiac Failure: 24 people, 32.43%
High Blood Cholesterol: 20 people, 27.03%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 19 people, 25.68%
Gout (uric acid crystals building up in the body): 19 people, 25.68%
Diarrhea: 19 people, 25.68%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 19 people, 25.68%
Multiple Myeloma (cancer of the plasma cells): 18 people, 24.32%
Atherosclerosis (disorder of the arteries): 17 people, 22.97%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 17 people, 22.97%

* Approximation only. Some reports may have incomplete information.

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