Edurant and Crixivan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Edurant (rilpivirine hydrochloride) and Crixivan (indinavir sulfate). Common drug interactions include quality of life decreased among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Edurant and Crixivan. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Edurant?

Edurant has active ingredients of rilpivirine hydrochloride. eHealthMe is studying from 2,238 Edurant users. Check the latest studies of Edurant.

What is Crixivan?

Crixivan has active ingredients of indinavir sulfate. eHealthMe is studying from 6,312 Crixivan users. Check the latest studies of Crixivan.

On Jul, 12, 2026

47 people who take Edurant and Crixivan together, and have interactions are studied.

What are the common drug interactions of Edurant and Crixivan, by gender? *:

female:

Quality of life decreased
Spinal compression fracture (fracture due to spinal compression on bone)
Visual acuity reduced (reduced clearness of vision)
Emotional distress
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)
Hip fracture

male:

Emotional distress
Pain
Mobility decreased (ability to move is reduced)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Bone loss
Decreased activity
Fatigue (feeling of tiredness)
Gait disturbance
Multiple fractures

What are the common drug interactions of Edurant and Crixivan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Emotional distress
Hypertensive nephropathy (hypertensive renal disease)
Osteomalacia (softening of the bones due to a lack of vitamin d)
Pain
Renal failure (kidney dysfunction)

40-49:

Quality of life decreased
Renal impairment (severely reduced kidney function)
Spinal compression fracture (fracture due to spinal compression on bone)
Upper limb fracture
Anxiety
Emotional distress
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depression
Osteopenia (a condition where bone mineral density is lower than normal)

50-59:

Emotional distress
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Depression
Hip fracture
Multiple fractures
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Decreased activity
Depression
Mobility decreased (ability to move is reduced)
Quality of life decreased
Renal cyst (kidney cyst)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

Hiv Infection: 45 people, 95.74%
High Blood Pressure: 8 people, 17.02%
High Blood Cholesterol: 7 people, 14.89%
Depression: 7 people, 14.89%
Stress And Anxiety: 6 people, 12.77%
Pain: 6 people, 12.77%
Laxative Supportive Care: 6 people, 12.77%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 6 people, 12.77%
Hypersensitivity: 5 people, 10.64%
Bacterial Infection: 5 people, 10.64%

* Approximation only. Some reports may have incomplete information.

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