Effexor xr and Demadex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor xr (venlafaxine hydrochloride) and Demadex (torsemide). Common drug interactions include choking among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Effexor xr and Demadex. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor xr?

Effexor xr has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 35,233 Effexor xr users. Check the latest studies of Effexor xr.

What is Demadex?

Demadex has active ingredients of torsemide. It is often used in heart failure. eHealthMe is studying from 5,358 Demadex users. Check the latest studies of Demadex.

On Jul, 08, 2026

54 people who take Effexor xr and Demadex together, and have interactions are studied.

Effexor xr and Demadex drug interactions.

What are the common drug interactions of Effexor Xr and Demadex, by gender? *:

female:

Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Chronic kidney disease
Congestive cardiomyopathy (weakening of heart muscle)
Coordination abnormal (abnormal movement)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diabetic coma
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diarrhoea

male:

Cardiac failure congestive
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Penile ulceration
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Sepsis (a severe blood infection that can lead to organ failure and death)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)

What are the common drug interactions of Effexor Xr and Demadex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Dyspnoea (difficult or laboured respiration)
Hallucination (an experience involving the perception of something not present)
Headache (pain in head)
Migraine (headache)
Pneumonia
Poor quality sleep
Retinal tear
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

Type 2 diabetes mellitus
Blood cholesterol increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dry mouth
Oropharyngeal pain
Pancreatitis (inflammation of pancreas)
Visual acuity reduced (reduced clearness of vision)
Chronic kidney disease
Diabetic coma
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)

50-59:

Relapsing-remitting multiple sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged)
Restless legs syndrome (a powerful urge to move your legs)
Restrictive pulmonary disease (reduction in total lung capacity)
Sedation
Sinusitis (inflammation of sinus)
Staphylococcal infection (an infection with staphylococcus bacteria)
Syncope (loss of consciousness with an inability to maintain postural tone)
Synovial cyst (cyst of joint filled with synovial fluid)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Thrombosis (formation of a blood clot inside a blood vessel)

60+:

Dyspnoea (difficult or laboured respiration)
Visual impairment
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Cardiac failure congestive
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Panic reaction
Type 2 diabetes mellitus
Disease progression
Drug ineffective
Dysphasia (language disorder marked by deficiency in the generation of speech)

What are the existing conditions these people have? *

Pain: 11 people, 20.37%
Suicidal Ideation: 10 people, 18.52%
Sleep Disorder: 9 people, 16.67%
Panic Disorder: 6 people, 11.11%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 6 people, 11.11%
Stress And Anxiety: 5 people, 9.26%
Migraine (headache): 5 people, 9.26%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 4 people, 7.41%
Headache (pain in head): 4 people, 7.41%
Type 2 Diabetes: 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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