Effexor xr and Questran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor xr (venlafaxine hydrochloride) and Questran (cholestyramine). Common drug interactions include rash among females and depressed level of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Effexor xr and Questran. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor xr?

Effexor xr has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 35,233 Effexor xr users. Check the latest studies of Effexor xr.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.



On Jul, 24, 2026

26 people who take Effexor xr and Questran together, and have interactions are studied.

Effexor xr and Questran drug interactions.

What are the common drug interactions of Effexor Xr and Questran, by gender? *:

female:

  1. Rash
  2. Pneumonia
  3. Cardiac arrest
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Drug dependence
  6. Hepatic fibrosis (scarring process that represents the liver's response to injury)
  7. Pain
  8. Pyrexia (fever)
  9. Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
  10. Hepatic steatosis (fatty liver disease)

male:

  1. Depressed level of consciousness
  2. Abdominal discomfort
  3. Pruritus (severe itching of the skin)
  4. Vomiting
  5. Abnormal behaviour
  6. Asthenia (weakness)
  7. Fall
  8. Fatigue (feeling of tiredness)
  9. Gastroenteritis (inflammation of stomach and intestine)
  10. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the common drug interactions of Effexor Xr and Questran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Suicidal ideation
  2. Migraine (headache)
  3. Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)

30-39:

n/a

40-49:

n/a

50-59:

  1. Cardiac arrest
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Drug dependence
  4. Hepatic fibrosis (scarring process that represents the liver's response to injury)
  5. Pain
  6. Pneumonia
  7. Pyrexia (fever)
  8. Rash
  9. Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
  10. Hepatic steatosis (fatty liver disease)

60+:

  1. Blood pressure increased
  2. Cataract (clouding of the lens inside the eye)
  3. Disease progression
  4. Dysarthria (speech disorder)
  5. Fall
  6. Gastroenteritis (inflammation of stomach and intestine)
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. Haemoglobin decreased
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  10. Hemiparesis (weakness on one side of the body)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 19.23%
  2. Multiple Myeloma (cancer of the plasma cells): 4 people, 15.38%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 15.38%
  4. Pain: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Effexor xr and Questran?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Effexor xr and Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Effexor xr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effexor xr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Questran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on venlafaxine hydrochloride and cholestyramine (the active ingredients of Effexor xr and Questran, respectively), and Effexor xr and Questran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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