Effexor xr and Risperdal consta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor xr (venlafaxine hydrochloride) and Risperdal consta (risperidone). Common drug interactions include tachycardia among females and pruritus among males.

The phase IV clinical study analyzes what interactions people have when they take Effexor xr and Risperdal consta. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor xr?

Effexor xr has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 35,233 Effexor xr users. Check the latest studies of Effexor xr.

What is Risperdal consta?

Risperdal consta has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 17,115 Risperdal consta users. Check the latest studies of Risperdal consta.



On Jul, 06, 2026

13 people who take Effexor xr and Risperdal consta together, and have interactions are studied.

Effexor xr and Risperdal consta drug interactions.

What are the common drug interactions of Effexor Xr and Risperdal Consta, by gender? *:

female:

  1. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  2. Angina pectoris (chest pain due to ischemia of the heart muscle)
  3. Asthenia (weakness)
  4. Cardiac arrest
  5. Cardiac murmur (an heart sound in valve abnormality)
  6. Cardiomyopathy (weakening of the heart muscle)
  7. Delirium (wild excitement)
  8. Eye disorder
  9. Fatigue (feeling of tiredness)
  10. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

male:

  1. Pruritus (severe itching of the skin)
  2. Urticaria (rash of round, red welts on the skin that itch intensely)
  3. Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
  4. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  5. Dyslipidaemia (abnormal amount of lipids)
  6. Hyperlipidaemia (presence of excess lipids in the blood)
  7. Impaired gastric emptying
  8. Neuropathy peripheral (surface nerve damage)
  9. Obesity (having too much body fat)
  10. Overdose

What are the common drug interactions of Effexor Xr and Risperdal Consta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pruritus (severe itching of the skin)
  2. Urticaria (rash of round, red welts on the skin that itch intensely)
  3. Blood cholesterol increased
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Diabetes mellitus inadequate control
  6. Diabetic gastroparesis (paralysis of the muscles of the stomach caused by diabetes)
  7. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  8. Dyslipidaemia (abnormal amount of lipids)
  9. Hyperlipidaemia (presence of excess lipids in the blood)
  10. Impaired gastric emptying

50-59:

  1. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  2. Feeling jittery
  3. Insomnia (sleeplessness)
  4. Psychomotor hyperactivity (feelings of extreme restlessness)
  5. Restlessness (not able to rest)

60+:

  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Asthenia (weakness)
  3. Incoherent (talking in a confused and unclear way)
  4. Jaundice neonatal (yellowing of skin in neonate)
  5. Lethargy (tiredness)
  6. Muscle rigidity (muscle stiffness)
  7. Myalgia (muscle pain)
  8. Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
  9. Overdose
  10. Poor weight gain neonatal

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 9 people, 69.23%
  2. Stress And Anxiety: 2 people, 15.38%
  3. Weight Loss: 1 person, 7.69%
  4. Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 1 person, 7.69%
  5. Psychotic Disorder: 1 person, 7.69%
  6. Parkinson's Disease: 1 person, 7.69%
  7. Pain: 1 person, 7.69%
  8. High Blood Pressure: 1 person, 7.69%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%
  10. Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Effexor xr and Risperdal consta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Effexor xr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Risperdal consta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effexor xr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Risperdal consta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on venlafaxine hydrochloride and risperidone (the active ingredients of Effexor xr and Risperdal consta, respectively), and Effexor xr and Risperdal consta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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