Effexor and Fanapt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor (venlafaxine hydrochloride) and Fanapt (iloperidone). Common drug interactions include insomnia among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Effexor and Fanapt. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

What is Fanapt?

Fanapt has active ingredients of iloperidone. It is often used in schizophrenia. eHealthMe is studying from 1,443 Fanapt users. Check the latest studies of Fanapt.

On Jul, 30, 2026

31 people who take Effexor and Fanapt together, and have interactions are studied.

What are the common drug interactions of Effexor and Fanapt, by gender? *:

female:

Insomnia (sleeplessness)
Weight increased
Chronic kidney disease
Heart rate increased
Renal injury (kidney injury)
Crying
Dyspnoea (difficult or laboured respiration)
Hunger
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Periodic limb movement disorder

male:

Drug ineffective
Initial insomnia (feeling of inadequate or poor-quality sleep)
Palpitations (feelings or sensations that your heart is pounding or racing)
Restlessness (not able to rest)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Somnolence (a state of near-sleep, a strong desire for sleep)
Surgery
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Priapism (prolonged and painful erection that can last from several hours up to a few days)
Asthenia (weakness)

What are the common drug interactions of Effexor and Fanapt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Heart rate increased
Hypotension (abnormally low blood pressure)

20-29:

Upper respiratory tract congestion
Oedema peripheral (superficial swelling)

30-39:

Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Oedema peripheral (superficial swelling)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Somnolence (a state of near-sleep, a strong desire for sleep)

40-49:

Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Priapism (prolonged and painful erection that can last from several hours up to a few days)
Tremor (trembling or shaking movements in one or more parts of your body)
Burning sensation
Ejaculation failure
Erectile dysfunction
Hallucination (an experience involving the perception of something not present)
Insomnia (sleeplessness)

50-59:

Fatigue (feeling of tiredness)
Heart rate increased
Hunger
Insomnia (sleeplessness)
Merycism (a rare disease in which food is chewed, swallowed, and then returned to the mouth and chewed again)
Muscle spasms (muscle contraction)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Periodic limb movement disorder
Pseudodementia (severe form of depression that results from a progressive brain disorder in which cognitive changes mimic those of dementia)

60+:

Chronic kidney disease
Renal injury (kidney injury)
Nephrogenic anaemia (anaemia due to kidney disease)
Urinary incontinence (inability to control the flow of urine and involuntary urination)

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 19.35%
Pain: 4 people, 12.90%
High Blood Cholesterol: 4 people, 12.90%
Sleep Disorder: 3 people, 9.68%
Insomnia (sleeplessness): 3 people, 9.68%
Nausea (feeling of having an urge to vomit): 2 people, 6.45%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 6.45%
Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood): 2 people, 6.45%
Hypertriglyceridaemia (excess of triglycerides in the blood): 2 people, 6.45%
Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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