Effexor and Multihance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor (venlafaxine hydrochloride) and Multihance (gadobenate dimeglumine). Common drug interactions include connective tissue disorder among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Effexor and Multihance. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,496 Effexor users. Check the latest studies of Effexor.

What is Multihance?

Multihance has active ingredients of gadobenate dimeglumine. eHealthMe is studying from 5,786 Multihance users. Check the latest studies of Multihance.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

41 people who take Effexor and Multihance together, and have interactions are studied.

Effexor and Multihance drug interactions.

What are the common drug interactions of Effexor and Multihance, by gender? *:

female:

Connective tissue disorder (any disease that has the connective tissues of the body)
Joint contracture (a permanent shortening of a muscle or joint)
Muscle contracture (a permanent shortening of a muscle)
Nausea (feeling of having an urge to vomit)
Skin fibrosis (fibrous tissue formation on skin)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Dry skin
Muscular weakness (muscle weakness)
Oedema (fluid collection in tissue)

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Deformity (disfigurement)
Discomfort
Emotional distress
Injury
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Rash
Scar
Dry skin

What are the common drug interactions of Effexor and Multihance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Nausea (feeling of having an urge to vomit)

30-39:

Laryngeal oedema (swelling of larynx)

40-49:

Contusion (a type of hematoma of tissue in which capillaries)
Muscular weakness (muscle weakness)
Abdominal pain upper
Anaphylactic reaction (serious allergic reaction)
Arthralgia (joint pain)
Balance disorder
Blood pressure inadequately controlled
Burning sensation
Cardiac arrest
Cellulitis (infection under the skin)

50-59:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
General physical health deterioration (weak health status)
Scar
Skin disorder (skin disease)
Skin hypertrophy (skin cells enlarges)
Skin tightness
Arthralgia (joint pain)
Deformity (disfigurement)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Mobility decreased (ability to move is reduced)

60+:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Hyperhidrosis (abnormally increased sweating)
Oropharyngeal discomfort (pain or irritation of oropharynx)
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Sneezing
Staring (a prolonged gaze or fixed look)
Nausea (feeling of having an urge to vomit)
Bradypnoea (an abnormally slow respiratory rate)
Cerebral hypoperfusion (a condition in which the brain doesn't get enough blood)

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 9 people, 21.95%
High Blood Pressure: 5 people, 12.20%
Pain: 4 people, 9.76%
Nuclear Magnetic Resonance Imaging Abdominal: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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