Effexor and Sirolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor (venlafaxine hydrochloride) and Sirolimus (sirolimus). Common drug interactions include abdominal rigidity among females and pulmonary oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Effexor and Sirolimus. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

What is Sirolimus?

Sirolimus has active ingredients of sirolimus. eHealthMe is studying from 11,823 Sirolimus users. Check the latest studies of Sirolimus.

On Aug, 04, 2026

22 people who take Effexor and Sirolimus together, and have interactions are studied.

Effexor and Sirolimus drug interactions.

What are the common drug interactions of Effexor and Sirolimus, by gender? *:

female:

Abdominal rigidity
Dizziness
Dysphonia (speech disorder attributable to a disorder of phonation)
Fall
Humerus fracture (injury to the upper arm bone)
Lethargy (tiredness)
Liver transplant rejection (failure of liver transplant)
Malaise (a feeling of general discomfort or uneasiness)
Non-cardiac chest pain
Pulmonary mycosis (lung infection caused by yeast-like fungi)

male:

Pulmonary oedema (fluid accumulation in the lungs)

What are the common drug interactions of Effexor and Sirolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal rigidity

30-39:

Asthenia (weakness)
Tremor (trembling or shaking movements in one or more parts of your body)
Abdominal pain upper
Non-cardiac chest pain
Abdominal pain
Chest pain

40-49:

n/a

50-59:

Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Scleroderma (hard skin)
Tremor (trembling or shaking movements in one or more parts of your body)

60+:

Fatigue (feeling of tiredness)
Abdominal discomfort
Nausea (feeling of having an urge to vomit)
Pulmonary mycosis (lung infection caused by yeast-like fungi)
Secretion discharge
Vomiting
Thrombocytopenia (decrease of platelets in blood)
Biliary cirrhosis primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver)
Blood phosphorus decreased
Death

What are the existing conditions these people have? *

Pain: 4 people, 18.18%
Fatigue (feeling of tiredness): 4 people, 18.18%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 4 people, 18.18%
Growth Hormone Deficiency: 4 people, 18.18%
High Blood Pressure: 3 people, 13.64%
Peripheral Swelling: 3 people, 13.64%
Blood Potassium Decreased: 3 people, 13.64%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 3 people, 13.64%
Diarrhea: 3 people, 13.64%
Blood Calcium Decreased: 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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