Effexor and Talwin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Effexor (venlafaxine hydrochloride) and Talwin (pentazocine lactate). Common drug interactions include headache among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Effexor and Talwin. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

What is Talwin?

Talwin has active ingredients of pentazocine lactate. It is often used in pain. eHealthMe is studying from 893 Talwin users. Check the latest studies of Talwin.



On Jul, 13, 2026

50 people who take Effexor and Talwin together, and have interactions are studied.

Effexor and Talwin drug interactions.

What are the common drug interactions of Effexor and Talwin, by gender? *:

female:

  1. Headache (pain in head)
  2. Hyperhidrosis (abnormally increased sweating)
  3. Bone disorder
  4. Bone loss
  5. Breast cancer recurrent
  6. Burning sensation
  7. Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
  8. Corneal deposits
  9. Cystitis bacterial (inflammation of the wall of the bladder by bacteria escherichia coli)
  10. Decreased interest

male:

  1. Back pain
  2. Headache (pain in head)
  3. Arthralgia (joint pain)
  4. Bacterial test positive
  5. Bipolar disorder (mood disorder)
  6. Blood cholesterol increased
  7. Bone disorder
  8. Bone loss
  9. Breast cancer recurrent
  10. Burning sensation

What are the common drug interactions of Effexor and Talwin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chest discomfort
  2. Cogwheel rigidity (tension in a muscle which gives way in little jerks when the muscle is stretched)
  3. Coma (state of unconsciousness lasting more than six hours)
  4. Complex partial seizures (epileptic seizure)
  5. Conjunctivitis (pink eye)
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Cough
  8. Dysarthria (speech disorder)
  9. Facial palsy (paralysis of face nerve)
  10. Fall

40-49:

  1. Drug hypersensitivity
  2. Alopecia (absence of hair from areas of the body)
  3. Back pain
  4. Bone disorder
  5. Bone loss
  6. Breast cancer recurrent
  7. Burning sensation
  8. Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
  9. Corneal deposits
  10. Cystitis bacterial (inflammation of the wall of the bladder by bacteria escherichia coli)

50-59:

  1. Drug hypersensitivity
  2. Transaminases increased
  3. Fall
  4. Tardive dyskinesia (a disorder that involves involuntary movements)
  5. Back pain
  6. Bacterial test positive
  7. Chronic kidney disease
  8. Coagulopathy (blood's ability to clot is impaired)
  9. Cough
  10. Decreased appetite

60+:

  1. Drug hypersensitivity
  2. Drug ineffective
  3. Breast discharge
  4. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  5. Coronary artery bypass
  6. Hypersensitivity
  7. Hypertension (high blood pressure)
  8. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
  9. Social avoidant behaviour (avoiding social connection a personality disorder)
  10. Decreased appetite

What are the existing conditions these people have? *

  1. Stress And Anxiety: 4 people, 8.00%
  2. Sleep Disorder: 4 people, 8.00%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 8.00%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.00%
  5. Insomnia (sleeplessness): 3 people, 6.00%
  6. High Blood Pressure: 3 people, 6.00%
  7. Breast Cancer: 3 people, 6.00%
  8. Back Pain: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Effexor and Talwin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Effexor and Talwin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Effexor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Talwin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effexor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Talwin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on venlafaxine hydrochloride and pentazocine lactate (the active ingredients of Effexor and Talwin, respectively), and Effexor and Talwin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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