Efudex and Ativan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Efudex (fluorouracil) and Ativan (lorazepam). Common drug interactions include abdominal pain among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Efudex and Ativan. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Efudex?

Efudex has active ingredients of fluorouracil. It is often used in actinic keratosis. eHealthMe is studying from 1,391 Efudex users. Check the latest studies of Efudex.

What is Ativan?

Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 78,506 Ativan users. Check the latest studies of Ativan.



On Jul, 06, 2026

55 people who take Efudex and Ativan together, and have interactions are studied.

Efudex and Ativan drug interactions.

What are the common drug interactions of Efudex and Ativan, by gender? *:

female:

  1. Abdominal pain
  2. Arthralgia (joint pain)
  3. Asthenia (weakness)
  4. Blood glucose increased
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Dyspnoea (difficult or laboured respiration)
  7. Hair disorder
  8. Hypertension (high blood pressure)
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Pain in jaw

male:

  1. Asthenia (weakness)
  2. Anaemia (lack of blood)
  3. Alcohol abuse
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Apnoea (suspension of external breathing)
  6. Arrhythmia (irregular heartbeat)
  7. Arthralgia (joint pain)
  8. Atelectasis (partial or complete collapse of the lung)
  9. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  10. Atrial tachycardia (rhythm disturbance that arises in the atria)

What are the common drug interactions of Efudex and Ativan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  3. Gastritis (inflammation of stomach)

40-49:

  1. Alopecia (absence of hair from areas of the body)
  2. Hair colour changes
  3. Hair disorder
  4. Abdominal pain
  5. Arrhythmia (irregular heartbeat)
  6. Aspartate aminotransferase increased
  7. Asthenia (weakness)
  8. Atelectasis (partial or complete collapse of the lung)
  9. Blood alkaline phosphatase increased
  10. Blood bilirubin increased

50-59:

  1. Abdominal pain
  2. Asthenia (weakness)
  3. Bone disorder
  4. Breast pain
  5. Dyspepsia (indigestion)
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Dyspnoea (difficult or laboured respiration)
  8. Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
  9. Hepatic cyst
  10. Hypersensitivity

60+:

  1. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  2. Asthenia (weakness)
  3. Heart rate increased
  4. Hypertension (high blood pressure)
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Seborrhoeic keratosis (noncancerous (benign) skin growths that some people develop as they age. they often appear on the back or chest)
  7. Hospitalisation
  8. Alcohol abuse
  9. Alopecia (absence of hair from areas of the body)
  10. Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 8 people, 14.55%
  2. Breast Cancer Female: 7 people, 12.73%
  3. Constipation: 6 people, 10.91%
  4. Rashes (redness): 5 people, 9.09%
  5. Pain: 4 people, 7.27%
  6. Metastases To Bone (cancer spreads to bone): 4 people, 7.27%
  7. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 5.45%
  8. Enlarged Prostate: 3 people, 5.45%
  9. Back Pain: 3 people, 5.45%
  10. Bone Disorder: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Do you take Efudex and Ativan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Efudex and Ativan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Efudex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ativan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Efudex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ativan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluorouracil and lorazepam (the active ingredients of Efudex and Ativan, respectively), and Efudex and Ativan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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