Efudex and Gabapentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Efudex (fluorouracil) and Gabapentin (gabapentin). Common drug interactions include alopecia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Efudex and Gabapentin. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Efudex?

Efudex has active ingredients of fluorouracil. It is often used in actinic keratosis. eHealthMe is studying from 1,391 Efudex users. Check the latest studies of Efudex.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 322,983 Gabapentin users. Check the latest studies of Gabapentin.

On Jul, 12, 2026

41 people who take Efudex and Gabapentin together, and have interactions are studied.

Efudex and Gabapentin drug interactions.

What are the common drug interactions of Efudex and Gabapentin, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Hair colour changes
Hair disorder
Anxiety
Drug ineffective
Erythema (redness of the skin)
Eye irritation
Surgery
Blood pressure increased
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Diarrhoea
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Application site discolouration
Application site scab (hard coating on the skin formed at application site)
Application site vesicles (small bubble within a cell at application site)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone density decreased
Bone loss
Chronic kidney disease

What are the common drug interactions of Efudex and Gabapentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone density decreased
Bone loss
Emotional distress
Hydronephrosis (water inside the kidney)
Nephrolithiasis (calculi in the kidneys)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis (death of bone)

50-59:

Anxiety
Surgery
Blood pressure increased
Chronic kidney disease
Delusion (a false belief or opinion)
Hallucination (an experience involving the perception of something not present)
Insomnia (sleeplessness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Renal failure (kidney dysfunction)

60+:

Alopecia (absence of hair from areas of the body)
Hair colour changes
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Drug dependence
Dyslipidaemia (abnormal amount of lipids)
Fall
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 36.59%
Pain: 6 people, 14.63%
High Blood Pressure: 4 people, 9.76%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.32%
Insomnia (sleeplessness): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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