Efudex and Pregabalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Efudex (fluorouracil) and Pregabalin (pregabalin). Common drug interactions include pyrexia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Efudex and Pregabalin. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Efudex?

Efudex has active ingredients of fluorouracil. It is often used in actinic keratosis. eHealthMe is studying from 1,391 Efudex users. Check the latest studies of Efudex.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,069 Pregabalin users. Check the latest studies of Pregabalin.

On Jul, 27, 2026

23 people who take Efudex and Pregabalin together, and have interactions are studied.

Efudex and Pregabalin drug interactions.

What are the common drug interactions of Efudex and Pregabalin, by gender? *:

female:

Pyrexia (fever)
Breast cancer metastatic
Breast cancer stage iv
Febrile neutropenia (fever with reduced white blood cells)
Hypoaesthesia (reduced sense of touch or sensation)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Staphylococcus test positive
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)

male:

Pneumonia
Road traffic accident
Headache (pain in head)
Neck pain
Spinal pain (pain in spine)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

What are the common drug interactions of Efudex and Pregabalin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

40-49:

n/a

50-59:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia
Pyrexia (fever)
Febrile neutropenia (fever with reduced white blood cells)

60+:

Pneumonia
Road traffic accident
Staphylococcus test positive
Localised infection (infection at the single location)
Pulmonary oedema (fluid accumulation in the lungs)
Breast cancer metastatic
Breast cancer stage iv
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 9 people, 39.13%
Multiple Myeloma (cancer of the plasma cells): 9 people, 39.13%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 17.39%
Ejection Fraction Decreased (systolic heart failure): 4 people, 17.39%
Rashes (redness): 2 people, 8.70%
Prostate Cancer: 2 people, 8.70%
Pain: 2 people, 8.70%
Neuralgia (pain in one or more nerves): 2 people, 8.70%
Constipation: 2 people, 8.70%
Chest Pain: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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