Efudex and Singulair drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Efudex (fluorouracil) and Singulair (montelukast sodium). Common drug interactions include blood pressure increased among females and basal cell carcinoma among males.

The phase IV clinical study analyzes what interactions people have when they take Efudex and Singulair. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Efudex?

Efudex has active ingredients of fluorouracil. It is often used in actinic keratosis. eHealthMe is studying from 1,391 Efudex users. Check the latest studies of Efudex.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

On Jul, 08, 2026

36 people who take Efudex and Singulair together, and have interactions are studied.

What are the common drug interactions of Efudex and Singulair, by gender? *:

female:

Blood pressure increased
Drug hypersensitivity
Headache (pain in head)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Neuropathy peripheral (surface nerve damage)
Pulmonary mass
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Vulvovaginal pain
Abdominal discomfort

male:

Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Benign neoplasm (benign (non-cancerous) tumour)
Pain
Skin burning sensation
Alcohol abuse
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Apnoea (suspension of external breathing)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)

What are the common drug interactions of Efudex and Singulair, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Alopecia (absence of hair from areas of the body)
Hair colour changes
Hair disorder

50-59:

Hypergonadism (hyperfunction of the gonads)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Pain
Spinal pain (pain in spine)
Thyroid mass
Visual impairment
Surgery

60+:

Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Benign neoplasm (benign (non-cancerous) tumour)
Dehydration (dryness resulting from the removal of water)
Fall
Skin burning sensation
Abdominal discomfort
Alcohol abuse
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 30.56%
Multiple Myeloma (cancer of the plasma cells): 5 people, 13.89%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 13.89%
Pain: 3 people, 8.33%
Insomnia (sleeplessness): 2 people, 5.56%
Immunodeficiency Common Variable: 2 people, 5.56%
Breast Cancer Metastatic: 2 people, 5.56%
Breast Cancer Female: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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