Efudex and Xalatan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Efudex (fluorouracil) and Xalatan (latanoprost). Common drug interactions include alopecia among females and metabolic encephalopathy among males.
The phase IV clinical study analyzes what interactions people have when they take Efudex and Xalatan. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Efudex?
Efudex has active ingredients of fluorouracil. It is often used in actinic keratosis. eHealthMe is studying from 1,391 Efudex users. Check the latest studies of Efudex.
What is Xalatan?
Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.
12 people who take Efudex and Xalatan together, and have interactions are studied.

What are the common drug interactions of Efudex and Xalatan, by gender? *:
female:
- Alopecia (absence of hair from areas of the body)
- Anxiety
- Emotional distress
- Pain
- Psychological trauma
male:
- Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
- Asthenia (weakness)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
- Death
- Constipation
- Dizziness postural
- Dyspnoea (difficult or laboured respiration)
- Heart rate irregular
- Hyperglycaemia (high blood sugar)
What are the common drug interactions of Efudex and Xalatan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
- Asthenia (weakness)
- Psychological trauma
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
- Death
- Alopecia (absence of hair from areas of the body)
- Anxiety
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
- Hyperglycaemia (high blood sugar)
What are the existing conditions these people have? *
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 33.33%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 25.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 16.67%
- Prostate Cancer: 2 people, 16.67%
- Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 16.67%
- Urinary Retention (the inability to completely or partially empty the bladder): 1 person, 8.33%
- Breast Cancer Female: 1 person, 8.33%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 8.33%
- Depression: 1 person, 8.33%
- Diabetes: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Efudex and Xalatan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Efudex and Xalatan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Efudex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xalatan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Efudex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xalatan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on fluorouracil and latanoprost (the active ingredients of Efudex and Xalatan, respectively), and Efudex and Xalatan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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