Elavil and Hc drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Elavil (amitriptyline hydrochloride) and Hc (hydrocortisone). Common drug interactions include back pain among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Elavil and Hc. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.

What is Hc?

Hc has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 1,369 Hc users. Check the latest studies of Hc.

On Jul, 26, 2026

29 people who take Elavil and Hc together, and have interactions are studied.

What are the common drug interactions of Elavil and Hc, by gender? *:

female:

Back pain
Chest pain
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Fall
Muscle spasms (muscle contraction)
Actinic keratosis (skin disease due to sun exposure)
Acute respiratory failure
Altered state of consciousness (altered state of mind)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

male:

Anxiety
Atelectasis (partial or complete collapse of the lung)
Thrombocytopenia (decrease of platelets in blood)
Cardiomegaly (increased size of heart than normal)
Hypoxia (low oxygen in tissues)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Pyrexia (fever)
Diarrhoea
Renal cyst (kidney cyst)

What are the common drug interactions of Elavil and Hc, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Actinic keratosis (skin disease due to sun exposure)
Acute respiratory failure
Altered state of consciousness (altered state of mind)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Back pain
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
Bladder diverticulum (pouch like projection in the bladder, by birth or acquired)

30-39:

Atelectasis (partial or complete collapse of the lung)
Drug addiction
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Urinary tract infection

40-49:

n/a

50-59:

Anaemia of malignant disease
Ankle fracture
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Atrioventricular block first degree (heart block first degree)

60+:

Anxiety
Atelectasis (partial or complete collapse of the lung)
Nephrolithiasis (calculi in the kidneys)
Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Pneumonia
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Pyrexia (fever)
Rectal haemorrhage (bleeding from anus)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 16 people, 55.17%
Bone Loss: 16 people, 55.17%
Neoplasm Malignant (cancer tumour): 8 people, 27.59%

* Approximation only. Some reports may have incomplete information.

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