Elavil and Invanz drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Elavil (amitriptyline hydrochloride) and Invanz (ertapenem sodium). Common drug interactions include gastric ulcer among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Elavil and Invanz. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Elavil?
Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.
What is Invanz?
Invanz has active ingredients of ertapenem sodium. It is often used in urinary tract infection. eHealthMe is studying from 3,961 Invanz users. Check the latest studies of Invanz.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
20 people who take Elavil and Invanz together, and have interactions are studied.

What are the common drug interactions of Elavil and Invanz, by gender? *:
female:
- Gastric ulcer (stomach ulcer)
- Malaise (a feeling of general discomfort or uneasiness)
- Pain
- Vomiting
- Ascites (accumulation of fluid in the abdominal cavity)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Chest discomfort
- Chills (felling of cold)
- Device occlusion
- Fatigue (feeling of tiredness)
male:
- Fall
- Asthenia (weakness)
What are the common drug interactions of Elavil and Invanz, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abasia (inability to walk)
- Asthenia (weakness)
- Dysarthria (speech disorder)
30-39:
n/a
40-49:
- Hypotension (abnormally low blood pressure)
- Pleural effusion (water on the lungs)
- Acute respiratory failure
- Cellulitis (infection under the skin)
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Fluid overload (too much fluid in the blood)
- Gastric ulcer (stomach ulcer)
- Malaise (a feeling of general discomfort or uneasiness)
- Pain
50-59:
- Chronic kidney disease
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
60+:
- Fall
- Tooth discolouration (a change in colour of teeth)
- Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Asthenia (weakness)
What are the existing conditions these people have? *
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 9 people, 45.00%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 25.00%
- Oedema (fluid collection in tissue): 5 people, 25.00%
- Constipation: 4 people, 20.00%
- Itching: 3 people, 15.00%
- Pain: 3 people, 15.00%
- Osteomyelitis (infection of bone): 3 people, 15.00%
- Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 2 people, 10.00%
- Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 10.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 10.00%
* Approximation only. Some reports may have incomplete information.
Do you take Elavil and Invanz?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Elavil and Invanz:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Elavil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Invanz:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Elavil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Invanz and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
- Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on amitriptyline hydrochloride and ertapenem sodium (the active ingredients of Elavil and Invanz, respectively), and Elavil and Invanz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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