Elavil and Prialt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Elavil (amitriptyline hydrochloride) and Prialt (ziconotide). Common drug interactions include nausea among females and memory impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Elavil and Prialt. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.

What is Prialt?

Prialt has active ingredients of ziconotide. It is often used in pain. eHealthMe is studying from 2,665 Prialt users. Check the latest studies of Prialt.



On Jul, 14, 2026

14 people who take Elavil and Prialt together, and have interactions are studied.

Elavil and Prialt drug interactions.

What are the common drug interactions of Elavil and Prialt, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Aphasia (damage to the parts of the brain that control language)
  3. Blood pressure increased
  4. Heart rate increased
  5. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  6. Arthralgia (joint pain)
  7. Back pain
  8. Diarrhoea
  9. Dysarthria (speech disorder)
  10. Dysgeusia (disorder of the sense of taste)

male:

  1. Memory impairment
  2. Anxiety
  3. Optic neuropathy (optic nerve damage)
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Photosensitivity reaction
  6. Vision blurred
  7. Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
  8. Aggression
  9. Apnoea (suspension of external breathing)
  10. Hallucination (an experience involving the perception of something not present)

What are the common drug interactions of Elavil and Prialt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anxiety
  2. Dehydration (dryness resulting from the removal of water)
  3. Panic attack

40-49:

  1. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  2. Arthralgia (joint pain)
  3. Back pain
  4. Diarrhoea
  5. Dysgeusia (disorder of the sense of taste)
  6. Energy increased
  7. Face injury
  8. Fall
  9. Fatigue (feeling of tiredness)
  10. Feeling jittery

50-59:

  1. Aphasia (damage to the parts of the brain that control language)
  2. Blood pressure increased
  3. Heart rate increased
  4. Nausea (feeling of having an urge to vomit)
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Vomiting

60+:

  1. Memory impairment
  2. Nausea (feeling of having an urge to vomit)
  3. Disturbance in attention
  4. Drug ineffective
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  6. Dysarthria (speech disorder)
  7. Dyspnoea (difficult or laboured respiration)
  8. Hallucination, auditory (perceiving sounds without auditory stimulus)
  9. Hypophagia (reduced food intake)
  10. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

What are the existing conditions these people have? *

  1. Spinal Pain (pain in spine): 2 people, 14.29%
  2. Post Laminectomy Syndrome: 2 people, 14.29%
  3. Spinal Osteoarthritis (joint cartilage loss in spine): 1 person, 7.14%
  4. Neuropathy Peripheral (surface nerve damage): 1 person, 7.14%
  5. Neuralgia (pain in one or more nerves): 1 person, 7.14%
  6. Muscle Spasms (muscle contraction): 1 person, 7.14%
  7. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 7.14%
  8. Herniated Nucleus Pulposus (Slipped Disk): 1 person, 7.14%
  9. Blood Testosterone Decreased: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Elavil and Prialt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Elavil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prialt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Elavil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prialt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amitriptyline hydrochloride and ziconotide (the active ingredients of Elavil and Prialt, respectively), and Elavil and Prialt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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