Elavil and Tekturna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Elavil (amitriptyline hydrochloride) and Tekturna (aliskiren hemifumarate). Common drug interactions include swollen tongue among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Elavil and Tekturna. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

On Aug, 06, 2026

12 people who take Elavil and Tekturna together, and have interactions are studied.

What are the common drug interactions of Elavil and Tekturna, by gender? *:

female:

Swollen tongue (swelling of tongue)
Adverse drug reaction
Cough
Drug effect decreased
Glossodynia (a burning or painful sensation in the tongue)
Muscle spasms (muscle contraction)
Oedema (fluid collection in tissue)
Pain
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Tongue oedema (swelling of tongue)

male:

Cellulitis (infection under the skin)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Back pain
Melaena (the passage of black, tarry stools)
Myalgia (muscle pain)
Renal failure (kidney dysfunction)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diarrhoea
Drug ineffective
Erythema (redness of the skin)

What are the common drug interactions of Elavil and Tekturna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Addison's disease (addison's disease, a hormonal disorder disease)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Adverse drug reaction
Application site erythema (redness of the skin at application site)
Application site pain
Application site rash
Application site swelling
Blood sodium decreased
Candidiasis (candidiasis or thrush is a fungal infection)
Dizziness

60+:

Cough
Cellulitis (infection under the skin)
Pain in extremity
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Pruritus generalised (generalized itching)
Swollen tongue (swelling of tongue)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Epistaxis (bleed from the nose)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 41.67%
Insomnia (sleeplessness): 4 people, 33.33%
High Blood Cholesterol: 2 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
Chest Pain: 2 people, 16.67%
Clostridial Infection (infectious conditions by clostridium bacteria): 2 people, 16.67%
Itching: 2 people, 16.67%
Swelling: 2 people, 16.67%
Diabetes: 2 people, 16.67%
Allergic Sinusitis: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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