Elidel and Desyrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Elidel (pimecrolimus) and Desyrel (trazodone hydrochloride). Common drug interactions include death among females and attention deficit hyperactivity disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Elidel and Desyrel. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Elidel?

Elidel has active ingredients of pimecrolimus. It is often used in eczema. eHealthMe is studying from 5,201 Elidel users. Check the latest studies of Elidel.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

On Jul, 19, 2026

21 people who take Elidel and Desyrel together, and have interactions are studied.

What are the common drug interactions of Elidel and Desyrel, by gender? *:

female:

Death
Neoplasm malignant (cancer tumour)
Speech disorder
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Confusional state
Cough
Lethargy (tiredness)
Malignant neoplasm progression (cancer tumour came back)
Mouth ulceration (mouth ulcers)
Oral candidiasis (fungal infection of mouth)

male:

Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
Blood cholesterol increased
Nasopharyngitis (inflammation of the nasopharynx)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Polycythaemia (proportion of blood volume that is occupied by red blood cells increases)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Sleep-related eating disorder (abnormal eating patterns during the night)
Snoring
Somnambulism (sleep walking)
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Elidel and Desyrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Foot deformity (functional disability of foot)
Impaired healing
Injection site bruising
Injection site pain
Loss of consciousness
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Procedural pain

40-49:

Hepatic steatosis (fatty liver disease)
Hypersomnia (excessive daytime sleepiness (eds))
Hypotension (abnormally low blood pressure)
Infection
Nasopharyngitis (inflammation of the nasopharynx)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Polycythaemia (proportion of blood volume that is occupied by red blood cells increases)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Sleep-related eating disorder (abnormal eating patterns during the night)
Snoring

50-59:

n/a

60+:

Actinomycosis (infection that causes sores, or abscesses)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Face oedema (swelling of face)
Gingival swelling (gums swelling)
Hyperplasia (enlargement of an organ or tissue)
Hypoaesthesia (reduced sense of touch or sensation)
Impaired healing
Inflammation
Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 14 people, 66.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 66.67%
Stress And Anxiety: 13 people, 61.90%
Breast Cancer: 13 people, 61.90%
Bone Pain: 13 people, 61.90%
Breast Cancer Metastatic: 6 people, 28.57%
Pain: 3 people, 14.29%
Nausea And Vomiting: 2 people, 9.52%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 9.52%
Intervertebral Disc Degeneration (spinal disc degeneration): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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