Eliquis and Ancef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eliquis (apixaban) and Ancef (cefazolin sodium). Common drug interactions include osteomyelitis among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Eliquis and Ancef. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,859 Eliquis users. Check the latest studies of Eliquis.

What is Ancef?

Ancef has active ingredients of cefazolin sodium. eHealthMe is studying from 3,292 Ancef users. Check the latest studies of Ancef.

On Jul, 19, 2026

22 people who take Eliquis and Ancef together, and have interactions are studied.

What are the common drug interactions of Eliquis and Ancef, by gender? *:

female:

Osteomyelitis (infection of bone)
Overdose
Pain in extremity
Pericardial effusion (fluid around the heart)
Pneumonia bacterial (pneumonia associated with bacterial infection)
Posterior capsule opacification
Pulmonary congestion (congestion in the lungs)
Rash
Rash erythematous (redness of the skin)
Red cell distribution width increased

male:

Fall
Fatigue (feeling of tiredness)
Chronic kidney disease
Renal failure (kidney dysfunction)
Cardiac arrest
Disturbance in attention
Lethargy (tiredness)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness

What are the common drug interactions of Eliquis and Ancef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Injection site extravasation (flow of (blood or lymph) from injection site)
Livedo reticularis (a lace-like purplish discoloration of the skin)
Localised infection (infection at the single location)
Lymphocyte percentage decreased
Muscular weakness (muscle weakness)
Necrosis (the death of body tissue)
Nodule (a growth of abnormal tissue)
Oral pain
Osteomyelitis (infection of bone)
Pain in extremity

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nephrogenic anaemia (anaemia due to kidney disease)

60+:

Fatigue (feeling of tiredness)
Hypotension (abnormally low blood pressure)
Cardiac failure
Cardiac failure acute
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Clostridium test positive
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)

What are the existing conditions these people have? *

Pain: 9 people, 40.91%
High Blood Pressure: 6 people, 27.27%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 22.73%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 22.73%
Constipation: 4 people, 18.18%
Blood Magnesium Decreased: 3 people, 13.64%
Endometrial Cancer: 3 people, 13.64%
Nausea And Vomiting: 3 people, 13.64%
Fever: 3 people, 13.64%
Gastric Ulcer (stomach ulcer): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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