Eliquis and Bendamustine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eliquis (apixaban) and Bendamustine (bendamustine). Common drug interactions include plasma cell myeloma among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Eliquis and Bendamustine. It is created by eHealthMe based on reports of 87 people who take the same drugs from the FDA, and is updated regularly.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,859 Eliquis users. Check the latest studies of Eliquis.

What is Bendamustine?

Bendamustine has active ingredients of bendamustine. eHealthMe is studying from 9,508 Bendamustine users. Check the latest studies of Bendamustine.



On Jul, 18, 2026

87 people who take Eliquis and Bendamustine together, and have interactions are studied.

Eliquis and Bendamustine drug interactions.

What are the common drug interactions of Eliquis and Bendamustine, by gender? *:

female:

  1. Plasma cell myeloma (cancer that begins in plasma cells)
  2. Pneumonia
  3. Pruritus (severe itching of the skin)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Sinusitis (inflammation of sinus)
  6. Aortic disorder
  7. Aortic valve incompetence
  8. Constipation
  9. Decreased appetite
  10. Disease progression

male:

  1. Pneumonia
  2. Pyrexia (fever)
  3. Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
  4. Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)
  5. Rash
  6. Subdural haematoma (blood collects between the skull and the surface of the brain)
  7. Alanine aminotransferase increased
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Fungal test positive
  10. Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)

What are the common drug interactions of Eliquis and Bendamustine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Abdominal distension
  2. Asthenia (weakness)
  3. Diarrhoea
  4. Flatulence (flatus expelled through the anus)
  5. Muscle spasms (muscle contraction)
  6. Neutropenia (an abnormally low number of neutrophils)

60+:

  1. Pneumonia
  2. Pyrexia (fever)
  3. Confusional state
  4. Hypotension (abnormally low blood pressure)
  5. Ascites (accumulation of fluid in the abdominal cavity)
  6. Asthenia (weakness)
  7. Chylothorax (collection of lymph fluid around the lung)
  8. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  9. Gamma-glutamyltransferase increased
  10. Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)

What are the existing conditions these people have? *

  1. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 25 people, 28.74%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 23 people, 26.44%
  3. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 14 people, 16.09%
  4. Constipation: 10 people, 11.49%
  5. Pain: 9 people, 10.34%
  6. Nausea (feeling of having an urge to vomit): 9 people, 10.34%
  7. High Blood Cholesterol: 8 people, 9.20%
  8. Enlarged Prostate: 7 people, 8.05%
  9. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 7 people, 8.05%
  10. Aortic Arteriosclerosis (hardening of the aortic arteries): 7 people, 8.05%

* Approximation only. Some reports may have incomplete information.

Do you take Eliquis and Bendamustine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Eliquis and Bendamustine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Eliquis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bendamustine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Eliquis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bendamustine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on apixaban and bendamustine (the active ingredients of Eliquis and Bendamustine, respectively), and Eliquis and Bendamustine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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