Eliquis and Dronedarone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Eliquis (apixaban) and Dronedarone (dronedarone). Common drug interactions include white blood cell count increased among females and dental caries among males.
The phase IV clinical study analyzes what interactions people have when they take Eliquis and Dronedarone. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Eliquis?
Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,861 Eliquis users. Check the latest studies of Eliquis.
What is Dronedarone?
Dronedarone has active ingredients of dronedarone. eHealthMe is studying from 509 Dronedarone users. Check the latest studies of Dronedarone.
35 people who take Eliquis and Dronedarone together, and have interactions are studied.

What are the common drug interactions of Eliquis and Dronedarone, by gender? *:
female:
- White blood cell count increased
- Abdominal distension
- Blood pressure decreased
- Cardiac disorder
- Discomfort
- Drug hypersensitivity
- Febrile neutropenia (fever with reduced white blood cells)
- Heart rate decreased
- Joint swelling
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
male:
- Dental caries
- Febrile neutropenia (fever with reduced white blood cells)
- Chest pain
- Circulatory collapse
- Death
- Diarrhoea
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Extrasystoles
- Hordeolum (small collection of pus (abscess) on the eyelid)
What are the common drug interactions of Eliquis and Dronedarone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Renal failure (kidney dysfunction)
50-59:
- Interstitial lung disease
- Iron deficiency anaemia
- Leukocytosis (increased white blood cells)
- Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
- Nausea (feeling of having an urge to vomit)
- Oesophageal dilatation (enlarged oesophagus)
- Oesophageal obstruction (blockage of oesophagus)
- Oropharyngeal pain
- Orthopnoea (shortness of breath (dyspnea) when lying down)
- Oxygen saturation decreased
60+:
- Fatigue (feeling of tiredness)
- Febrile neutropenia (fever with reduced white blood cells)
- Hypoaesthesia (reduced sense of touch or sensation)
- Peripheral swelling
- Bone disorder
- Decreased appetite
- Dyspnoea (difficult or laboured respiration)
- Gait disturbance
- Gastric haemorrhage (bleeding stomach)
- Goodpasture's syndrome (immune system mistakenly attacks and destroys healthy body tissue)
What are the existing conditions these people have? *
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 14.29%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 11.43%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 11.43%
- Multiple Myeloma (cancer of the plasma cells): 3 people, 8.57%
- Pain: 2 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Eliquis and Dronedarone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Eliquis (191,861 reports)
- Dronedarone (509 reports)
Browse all drug interactions of Eliquis and Dronedarone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Eliquis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dronedarone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Eliquis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dronedarone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on apixaban and dronedarone (the active ingredients of Eliquis and Dronedarone, respectively), and Eliquis and Dronedarone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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