Eliquis and Relistor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eliquis (apixaban) and Relistor (methylnaltrexone bromide). Common drug interactions include arthralgia among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Eliquis and Relistor. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,859 Eliquis users. Check the latest studies of Eliquis.

What is Relistor?

Relistor has active ingredients of methylnaltrexone bromide. eHealthMe is studying from 1,659 Relistor users. Check the latest studies of Relistor.

On Jul, 15, 2026

22 people who take Eliquis and Relistor together, and have interactions are studied.

What are the common drug interactions of Eliquis and Relistor, by gender? *:

female:

Arthralgia (joint pain)
Abdominal distension
Constipation
Diarrhoea
Drug ineffective
Fatigue (feeling of tiredness)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Vomiting
Abnormal dreams

male:

Abdominal distension
Constipation
Abdominal pain upper
Balance disorder
Chronic kidney disease
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Cough
Device dislocation
Drug ineffective
Dyskinesia (abnormality or impairment of voluntary movement)

What are the common drug interactions of Eliquis and Relistor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Constipation
Diarrhoea
Dizziness
Dry mouth
Ear infection
Eye swelling
Flushing (the warm, red condition of human skin)
Nausea (feeling of having an urge to vomit)
Pain
Vomiting

50-59:

Arthralgia (joint pain)
Bone pain
Constipation
Disturbance in attention
Fatigue (feeling of tiredness)
Headache (pain in head)
Insomnia (sleeplessness)
Peripheral swelling
Thrombosis (formation of a blood clot inside a blood vessel)

60+:

Diarrhoea
Drug ineffective
Abnormal dreams
Anorectal discomfort
Balance disorder
Bladder discomfort
Chronic kidney disease
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Decreased appetite
Eating disorder

What are the existing conditions these people have? *

Constipation: 10 people, 45.45%
Renal Cell Carcinoma (a kidney cancer): 2 people, 9.09%
Pain: 2 people, 9.09%
Orchitis (inflammation of the testes): 2 people, 9.09%
Multiple Myeloma (cancer of the plasma cells): 2 people, 9.09%
Lung Infection: 2 people, 9.09%
Irritable Bowel Syndrome: 2 people, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.09%
Cytomegalovirus Infection: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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