Eliquis and Versed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eliquis (apixaban) and Versed (midazolam hydrochloride). Common drug interactions include pulmonary arterial hypertension among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Eliquis and Versed. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,861 Eliquis users. Check the latest studies of Eliquis.

What is Versed?

Versed has active ingredients of midazolam hydrochloride. It is often used in sedation during medical procedure. eHealthMe is studying from 6,869 Versed users. Check the latest studies of Versed.

On Aug, 02, 2026

31 people who take Eliquis and Versed together, and have interactions are studied.

What are the common drug interactions of Eliquis and Versed, by gender? *:

female:

Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Renal vein thrombosis (blood clot in renal vein)
Rib fracture
Right ventricular failure (right half of the heart fails to work)
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight increased
Acute respiratory failure
Blood cholesterol increased
C-reactive protein increased
Colitis (inflammation of colon)

male:

Acute myocardial infarction (acute heart attack)
Acute respiratory failure
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)
Cardiac arrest
Disturbance in attention
Lethargy (tiredness)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)

What are the common drug interactions of Eliquis and Versed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pain
Pyrexia (fever)
Spinal cord compression
Splenic lesion (lesion on spleen)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Wound
Pelvic abscess
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Chronic kidney disease
Depression suicidal (suicide depressive disorder)
Emotional distress
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Renal failure (kidney dysfunction)

60+:

Lung infection
Nasopharyngitis (inflammation of the nasopharynx)
Fluid overload (too much fluid in the blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Labile blood pressure (wildly fluctuating blood pressure)
Renal failure (kidney dysfunction)
Pericardial effusion (fluid around the heart)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain
Cardiac disorder

What are the existing conditions these people have? *

Pain: 10 people, 32.26%
High Blood Pressure: 9 people, 29.03%
Nausea (feeling of having an urge to vomit): 8 people, 25.81%
Abdominal Pain: 5 people, 16.13%
Constipation: 5 people, 16.13%
Stress And Anxiety: 5 people, 16.13%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 4 people, 12.90%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.90%
Pelvic Abscess: 4 people, 12.90%
Ovarian Cancer (cancer of ovary): 4 people, 12.90%

* Approximation only. Some reports may have incomplete information.

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