Elmiron and Ranexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Elmiron (pentosan polysulfate sodium) and Ranexa (ranolazine). Common drug interactions include renal disorder among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Elmiron and Ranexa. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Elmiron?

Elmiron has active ingredients of pentosan polysulfate sodium. It is often used in interstitial cystitis (ic). eHealthMe is studying from 10,215 Elmiron users. Check the latest studies of Elmiron.

What is Ranexa?

Ranexa has active ingredients of ranolazine. It is often used in angina. eHealthMe is studying from 11,758 Ranexa users. Check the latest studies of Ranexa.

On Jul, 15, 2026

18 people who take Elmiron and Ranexa together, and have interactions are studied.

What are the common drug interactions of Elmiron and Ranexa, by gender? *:

female:

Renal disorder (kidney disease)
Road traffic accident
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Age-related macular degeneration
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cardiac disorder
Retinal pigmentation (pigmentation of retina)
Visual impairment
Hypertension (high blood pressure)

male:

Death
Plasma cell myeloma (cancer that begins in plasma cells)

What are the common drug interactions of Elmiron and Ranexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Age-related macular degeneration

60+:

Age-related macular degeneration
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
Death
Plasma cell myeloma (cancer that begins in plasma cells)

What are the existing conditions these people have? *

Cystitis Interstitial (unknown cause characterized by bladder pain): 10 people, 55.56%
Cardiac Disorder: 7 people, 38.89%
High Blood Cholesterol: 7 people, 38.89%
High Blood Pressure: 6 people, 33.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 22.22%
Gastric Disorder (disease of stomach): 3 people, 16.67%
Injury: 3 people, 16.67%
Chest Pain: 3 people, 16.67%
Depression: 3 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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