Embeda and Phenergan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Embeda (morphine sulfate; naltrexone hydrochloride) and Phenergan (promethazine hydrochloride). Common drug interactions include contusion among females and ageusia among males.

The phase IV clinical study analyzes what interactions people have when they take Embeda and Phenergan. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Embeda?

Embeda has active ingredients of morphine sulfate; naltrexone hydrochloride. eHealthMe is studying from 1,407 Embeda users. Check the latest studies of Embeda.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 25,312 Phenergan users. Check the latest studies of Phenergan.

On Jul, 10, 2026

18 people who take Embeda and Phenergan together, and have interactions are studied.

What are the common drug interactions of Embeda and Phenergan, by gender? *:

female:

Contusion (a type of hematoma of tissue in which capillaries)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal discomfort
Anxiety
Bile duct stone
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Coma (state of unconsciousness lasting more than six hours)
Crying
Depression
Dyskinesia (abnormality or impairment of voluntary movement)

male:

Ageusia (loss of taste functions of the tongue)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Decreased appetite
Dysgeusia (disorder of the sense of taste)
Dysphonia (speech disorder attributable to a disorder of phonation)
Hepatic enzyme increased
Memory impairment
Oropharyngeal pain
Tooth disorder (tooth disease)
Weight decreased

What are the common drug interactions of Embeda and Phenergan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cardiac arrest
Diarrhoea
Hemiplegic migraine (migraine attacks occurring in two or more people in the same family who experience weakness on one side of body)
Memory impairment
Sepsis (a severe blood infection that can lead to organ failure and death)

40-49:

Migraine (headache)
Upper respiratory tract infection

50-59:

Burning sensation
Contusion (a type of hematoma of tissue in which capillaries)
Muscle spasms (muscle contraction)
Varicose vein ruptured

60+:

Abdominal discomfort
Anxiety
Fatigue (feeling of tiredness)
Head injury
Headache (pain in head)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Malaise (a feeling of general discomfort or uneasiness)
Nightmare (unpleasant dream)
Personality change
Post-traumatic stress disorder

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 33.33%
Pain: 5 people, 27.78%
Renal Cell Carcinoma (a kidney cancer): 3 people, 16.67%
Vitamin B12 Deficiency: 2 people, 11.11%
Thyroid Diseases: 2 people, 11.11%
Cardiac Disorder: 2 people, 11.11%
Depression: 2 people, 11.11%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 11.11%
High Blood Cholesterol: 2 people, 11.11%
High Blood Pressure: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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