Embolex and Isoptin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Embolex (dihydroergotamine mesylate; heparin sodium; lidocaine hydrochloride) and Isoptin (verapamil hydrochloride). Common drug interactions include renal failure among females and cardiac failure among males.

The phase IV clinical study analyzes what interactions people have when they take Embolex and Isoptin. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Embolex?

Embolex has active ingredients of dihydroergotamine mesylate; heparin sodium; lidocaine hydrochloride. eHealthMe is studying from 1,161 Embolex users. Check the latest studies of Embolex.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.

On Jul, 13, 2026

26 people who take Embolex and Isoptin together, and have interactions are studied.

What are the common drug interactions of Embolex and Isoptin, by gender? *:

female:

Renal failure (kidney dysfunction)
Brain injury
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Pneumonia
Pruritus (severe itching of the skin)
Leukocytosis (increased white blood cells)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Rash
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood creatinine increased

male:

Cardiac failure
Dyspnoea (difficult or laboured respiration)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Mouth ulceration (mouth ulcers)
Mucous membrane disorder (disease of mucous membrane)
Oedema (fluid collection in tissue)
Skin disorder (skin disease)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Oedema lower limb (fluid collection in tissue of lower leg)

What are the common drug interactions of Embolex and Isoptin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Brain injury
Renal failure (kidney dysfunction)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Pneumonia
Leukocytosis (increased white blood cells)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Pruritus (severe itching of the skin)
Rash
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood creatinine increased

60+:

Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Cardiac failure
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood creatinine increased
Blood lactate dehydrogenase increased
Brain hypoxia (reduced supply of oxygen to the brain)
Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Laboratory test abnormal
Mouth ulceration (mouth ulcers)

What are the existing conditions these people have? *

Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 20 people, 76.92%
Fever: 20 people, 76.92%
Acute Kidney Failure: 20 people, 76.92%
Anaemia (lack of blood): 20 people, 76.92%
Arrhythmias (irregular heartbeat): 20 people, 76.92%
Constipation: 20 people, 76.92%
Infection: 20 people, 76.92%
Heart Disease: 20 people, 76.92%
Sleep Disorder: 20 people, 76.92%
Cough: 18 people, 69.23%

* Approximation only. Some reports may have incomplete information.

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