Emend and Asacol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emend (aprepitant) and Asacol (mesalamine). Common drug interactions include alopecia among females.

The phase IV clinical study analyzes what interactions people have when they take Emend and Asacol. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Emend?

Emend has active ingredients of aprepitant. It is often used in nausea. eHealthMe is studying from 13,741 Emend users. Check the latest studies of Emend.

What is Asacol?

Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.

On Jul, 14, 2026

59 people who take Emend and Asacol together, and have interactions are studied.

What are the common drug interactions of Emend and Asacol, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Anti-cyclic citrullinated peptide antibody positive
Hepatic enzyme increased
Infection
Joint swelling
Arthralgia (joint pain)
Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
Fatigue (feeling of tiredness)
Glossodynia (a burning or painful sensation in the tongue)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)

male:

n/a

What are the common drug interactions of Emend and Asacol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Facet joint syndrome (problem with movement of the facet joints of the spine)
Inflammation
Injury
Lung disorder (lung disease)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pneumonia
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Alopecia (absence of hair from areas of the body)
Anti-cyclic citrullinated peptide antibody positive

50-59:

Arthralgia (joint pain)
Breast pain
Stomatitis (inflammation of mucous membrane of mouth)
Syncope (loss of consciousness with an inability to maintain postural tone)
Tinnitus (a ringing in the ears)
Tongue ulceration (ulcers on tongue)
Chest pain
Death
Dizziness
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

n/a

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 56 people, 94.92%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 55 people, 93.22%
Psoriasis (immune-mediated disease that affects the skin): 43 people, 72.88%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 38 people, 64.41%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 35 people, 59.32%
Synovitis (inflammation of the synovial membrane): 28 people, 47.46%
Inflammation: 28 people, 47.46%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 27 people, 45.76%
Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 26 people, 44.07%
Pain: 25 people, 42.37%

* Approximation only. Some reports may have incomplete information.

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