Emla and Innohep drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Emla (lidocaine; prilocaine) and Innohep (tinzaparin sodium). Common drug interactions include bronchiolitis among females and cutaneous lupus erythematosus among males.
The phase IV clinical study analyzes what interactions people have when they take Emla and Innohep. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Emla?
Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.
What is Innohep?
Innohep has active ingredients of tinzaparin sodium. eHealthMe is studying from 9,243 Innohep users. Check the latest studies of Innohep.
34 people who take Emla and Innohep together, and have interactions are studied.

What are the common drug interactions of Emla and Innohep, by gender? *:
female:
- Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
- Decreased appetite
- Dyspnoea (difficult or laboured respiration)
- Melaena (the passage of black, tarry stools)
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Anaemia (lack of blood)
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Hepatocellular injury (liver injury)
male:
- Cutaneous lupus erythematosus (own immune system attacks various cells causing a wide variety of signs and symptoms)
- Pyrexia (fever)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
- Liver disorder (liver diseases)
- Renal failure (kidney dysfunction)
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
- Nausea (feeling of having an urge to vomit)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Anastomotic ulcer
What are the common drug interactions of Emla and Innohep, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Pyrexia (fever)
- Anastomotic ulcer
- Haematochezia (passage of stools containing blood)
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Diarrhoea
- Melaena (the passage of black, tarry stools)
- Nausea (feeling of having an urge to vomit)
- Vomiting
60+:
- Nausea (feeling of having an urge to vomit)
- Cutaneous lupus erythematosus (own immune system attacks various cells causing a wide variety of signs and symptoms)
- Hyperthermia (body temperature greatly above normal)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Interstitial lung disease
- Liver disorder (liver diseases)
- Melaena (the passage of black, tarry stools)
- Renal failure (kidney dysfunction)
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
- Vomiting
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 20 people, 58.82%
- Depression: 18 people, 52.94%
- Sleep Disorder: 17 people, 50.00%
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 17 people, 50.00%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 17 people, 50.00%
- Muscle Spasms (muscle contraction): 17 people, 50.00%
- High Blood Pressure: 5 people, 14.71%
- Diarrhea: 4 people, 11.76%
- Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 3 people, 8.82%
- Local Anaesthesia: 3 people, 8.82%
* Approximation only. Some reports may have incomplete information.
Do you take Emla and Innohep?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Emla and Innohep:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Emla:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Innohep:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Emla and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Innohep and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lidocaine; prilocaine and tinzaparin sodium (the active ingredients of Emla and Innohep, respectively), and Emla and Innohep (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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