Emla and Vfend drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emla (lidocaine; prilocaine) and Vfend (voriconazole). Common drug interactions include sepsis among females and alcohol abuse among males.

The phase IV clinical study analyzes what interactions people have when they take Emla and Vfend. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Emla?

Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.

What is Vfend?

Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.

On Jul, 12, 2026

18 people who take Emla and Vfend together, and have interactions are studied.

What are the common drug interactions of Emla and Vfend, by gender? *:

female:

Sepsis (a severe blood infection that can lead to organ failure and death)
Leukaemia recurrent (repeat cancer of bone marrow or blood cells)
Colitis (inflammation of colon)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Decreased appetite
Disease recurrence
Hypoxia (low oxygen in tissues)
Nausea (feeling of having an urge to vomit)
Stomatitis (inflammation of mucous membrane of mouth)

male:

Alcohol abuse
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Abdominal pain
Constipation
Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Rash pruritic (redness with itching)
Skin burning sensation
Terminal state (the transitional states between life and biological death)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Emla and Vfend, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Decreased appetite
Hypoxia (low oxygen in tissues)
Nausea (feeling of having an urge to vomit)
Stomatitis (inflammation of mucous membrane of mouth)
Streptococcal infection

10-19:

Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperkalaemia (damage to or disease of the kidney)
Pneumonia

20-29:

n/a

30-39:

n/a

40-49:

Alcohol abuse
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Lung abscess (pus in lungs)

50-59:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
White blood cell count decreased

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Leukaemia recurrent (repeat cancer of bone marrow or blood cells)
Rash pruritic (redness with itching)
Skin burning sensation
Colitis (inflammation of colon)
Herpes zoster
Weight increased
Abdominal pain
Constipation
Disease recurrence

What are the existing conditions these people have? *

Pain: 10 people, 55.56%
Constipation: 9 people, 50.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 8 people, 44.44%
Nausea (feeling of having an urge to vomit): 7 people, 38.89%
Insomnia (sleeplessness): 6 people, 33.33%
Nausea And Vomiting: 4 people, 22.22%
High Blood Pressure: 4 people, 22.22%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 4 people, 22.22%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 16.67%
Fungal Infection: 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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