Emtricitabine and Harvoni drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emtricitabine (emtricitabine) and Harvoni (ledipasvir; sofosbuvir). Common drug interactions include anxiety among females and congestive cardiomyopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Emtricitabine and Harvoni. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Emtricitabine?

Emtricitabine has active ingredients of emtricitabine. eHealthMe is studying from 6,391 Emtricitabine users. Check the latest studies of Emtricitabine.

What is Harvoni?

Harvoni has active ingredients of ledipasvir; sofosbuvir. eHealthMe is studying from 19,858 Harvoni users. Check the latest studies of Harvoni.



On Jul, 17, 2026

15 people who take Emtricitabine and Harvoni together, and have interactions are studied.

Emtricitabine and Harvoni drug interactions.

What are the common drug interactions of Emtricitabine and Harvoni, by gender? *:

female:

  1. Anxiety
  2. Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
  3. Crying
  4. Depressive symptom
  5. Diarrhoea
  6. Initial insomnia (feeling of inadequate or poor-quality sleep)
  7. Mood altered (changes in mood)
  8. Nervousness
  9. Osteoporosis (bones weak and more likely to break)
  10. Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)

male:

  1. Congestive cardiomyopathy (weakening of heart muscle)
  2. Drug resistance (reduction in effectiveness of a drug)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Substance-induced psychotic disorder
  5. Neoplasm malignant (cancer tumour)
  6. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  7. Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
  8. Blood bilirubin increased
  9. Drug ineffective
  10. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)

What are the common drug interactions of Emtricitabine and Harvoni, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Congestive cardiomyopathy (weakening of heart muscle)
  2. Drug resistance (reduction in effectiveness of a drug)
  3. Neoplasm malignant (cancer tumour)
  4. Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
  5. Drug ineffective
  6. Hepatitis c
  7. Substance-induced psychotic disorder

50-59:

  1. Initial insomnia (feeling of inadequate or poor-quality sleep)
  2. Mood altered (changes in mood)
  3. Nervousness
  4. Osteoporosis (bones weak and more likely to break)
  5. Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
  6. Sleep disorder
  7. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  8. Anxiety
  9. Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
  10. Crying

60+:

  1. Blood bilirubin increased
  2. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  3. Fatigue (feeling of tiredness)
  4. Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

  1. Hiv Infection: 11 people, 73.33%
  2. Hepatitis C: 11 people, 73.33%
  3. Type 2 Diabetes: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Emtricitabine and Harvoni?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Emtricitabine and Harvoni:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Emtricitabine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Harvoni:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Emtricitabine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Harvoni and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on emtricitabine and ledipasvir; sofosbuvir (the active ingredients of Emtricitabine and Harvoni, respectively), and Emtricitabine and Harvoni (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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