Emtriva and Prezcobix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Emtriva (emtricitabine) and Prezcobix (cobicistat; darunavir ethanolate). Common drug interactions include hyperkalaemia among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Emtriva and Prezcobix. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Emtriva?

Emtriva has active ingredients of emtricitabine. eHealthMe is studying from 2,383 Emtriva users. Check the latest studies of Emtriva.

What is Prezcobix?

Prezcobix has active ingredients of cobicistat; darunavir ethanolate. eHealthMe is studying from 2,113 Prezcobix users. Check the latest studies of Prezcobix.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

68 people who take Emtriva and Prezcobix together, and have interactions are studied.

Emtriva and Prezcobix drug interactions.

What are the common drug interactions of Emtriva and Prezcobix, by gender? *:

female:

Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
Bone density decreased
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Mobility decreased (ability to move is reduced)
Osteonecrosis (death of bone)
Osteoporosis (bones weak and more likely to break)
Arthralgia (joint pain)
Bone loss
Drug ineffective

male:

Emotional distress
Pain
Osteoporosis (bones weak and more likely to break)
Quality of life decreased
Renal impairment (severely reduced kidney function)
Blood creatinine increased
Bone density decreased
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Drug ineffective

What are the common drug interactions of Emtriva and Prezcobix, by age (0-1 to 60+)? *:

0-1:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Blood creatinine increased
Body height decreased
Bone pain
Emotional distress
Fatigue (feeling of tiredness)
Gait disturbance
Osteopenia (a condition where bone mineral density is lower than normal)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Emotional distress
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depression
Bone density decreased
Osteoporosis (bones weak and more likely to break)
Blood creatinine increased
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

40-49:

Renal impairment (severely reduced kidney function)
Anaemia (lack of blood)
Decreased activity
Osteoporosis (bones weak and more likely to break)
Blood creatinine increased
Depression
Drug ineffective
Dysuria (painful or difficult urination)
Fall
Foot fracture

50-59:

Pain
Chronic kidney disease
Emotional distress
Anxiety
Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depression
Osteonecrosis (death of bone)
Bone loss
Drug ineffective

60+:

Chronic kidney disease
Emotional distress
Blood creatinine increased
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Gait disturbance
Malaise (a feeling of general discomfort or uneasiness)
Renal impairment (severely reduced kidney function)
Nephrogenic anaemia (anaemia due to kidney disease)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Bone density decreased

What are the existing conditions these people have? *

Hiv Infection: 66 people, 97.06%
Pain: 9 people, 13.24%
High Blood Pressure: 8 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 11.76%
High Blood Cholesterol: 6 people, 8.82%
Hypersensitivity: 5 people, 7.35%
Herpes Virus Infection: 5 people, 7.35%
Diabetes: 5 people, 7.35%
Depression: 5 people, 7.35%
Asthma: 5 people, 7.35%

* Approximation only. Some reports may have incomplete information.

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