Enablex and Clotrimazole drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Enablex (darifenacin hydrobromide) and Clotrimazole (clotrimazole). Common drug interactions include gait disturbance among females and pyelonephritis among males.
The phase IV clinical study analyzes what interactions people have when they take Enablex and Clotrimazole. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Enablex?
Enablex has active ingredients of darifenacin hydrobromide. It is often used in urge incontinence. eHealthMe is studying from 4,934 Enablex users. Check the latest studies of Enablex.
What is Clotrimazole?
Clotrimazole has active ingredients of clotrimazole. It is often used in thrush. eHealthMe is studying from 13,947 Clotrimazole users. Check the latest studies of Clotrimazole.
25 people who take Enablex and Clotrimazole together, and have interactions are studied.

What are the common drug interactions of Enablex and Clotrimazole, by gender? *:
female:
- Gait disturbance
- Herpes zoster
- Hypoaesthesia (reduced sense of touch or sensation)
- Insomnia (sleeplessness)
- Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
- Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
- Muscular weakness (muscle weakness)
- Ocular hyperaemia (an abnormally large amount of blood in eye)
- Photophobia (extreme sensitivity to light)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
male:
- Pyelonephritis (inflammation of kidney caused by bacteria)
- Urinary retention (the inability to completely or partially empty the bladder)
- Glomerular filtration rate decreased
What are the common drug interactions of Enablex and Clotrimazole, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abasia (inability to walk)
- Ammonia increased
- Cellulitis (infection under the skin)
- Gastric haemorrhage (bleeding stomach)
- Hepatic failure (liver failure)
- Neuropathy peripheral (surface nerve damage)
- Pain
- Pelvic haemorrhage (pelvic bleeding)
- Pelvic mass
- Stomach mass
40-49:
- Cellulitis (infection under the skin)
- Chronic kidney disease
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Dyskinesia (abnormality or impairment of voluntary movement)
- Dyspnoea (difficult or laboured respiration)
- Hypotension (abnormally low blood pressure)
- Hypotonia (low muscle tone)
- Mydriasis (a dilation of the pupil)
- Nausea (feeling of having an urge to vomit)
50-59:
- Fatigue (feeling of tiredness)
- Gait disturbance
- Herpes zoster
- Hypoaesthesia (reduced sense of touch or sensation)
- Insomnia (sleeplessness)
- Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
- Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
- Muscular weakness (muscle weakness)
- Ocular hyperaemia (an abnormally large amount of blood in eye)
- Photophobia (extreme sensitivity to light)
60+:
- Pyelonephritis (inflammation of kidney caused by bacteria)
- Urinary retention (the inability to completely or partially empty the bladder)
- Glomerular filtration rate decreased
- Fall
- Urinary tract infection
What are the existing conditions these people have? *
- Pain: 11 people, 44.00%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 36.00%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 7 people, 28.00%
- Diabetes: 7 people, 28.00%
- Inflammation: 4 people, 16.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.00%
- Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 16.00%
- Sleep Disorder: 2 people, 8.00%
- Skin Irritation: 2 people, 8.00%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Enablex and Clotrimazole?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Enablex (4,934 reports)
- Clotrimazole (13,947 reports)
Browse all drug interactions of Enablex and Clotrimazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Enablex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clotrimazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Enablex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clotrimazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on darifenacin hydrobromide and clotrimazole (the active ingredients of Enablex and Clotrimazole, respectively), and Enablex and Clotrimazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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