Enablex and Losartan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enablex (darifenacin hydrobromide) and Losartan (losartan potassium). Common drug interactions include anaemia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Enablex and Losartan. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Enablex?

Enablex has active ingredients of darifenacin hydrobromide. It is often used in urge incontinence. eHealthMe is studying from 4,934 Enablex users. Check the latest studies of Enablex.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.

On Jul, 28, 2026

84 people who take Enablex and Losartan together, and have interactions are studied.

What are the common drug interactions of Enablex and Losartan, by gender? *:

female:

Anaemia (lack of blood)
Anxiety
Arthropathy
Blood creatinine increased
Blood pressure systolic increased
Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Hallucination, visual (seeing things that aren't there)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Blood pressure decreased
Carotid artery occlusion (artery blockage)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Colonic polyp (extra part of colon tissue grow in intestine)
Constipation
Decreased appetite

What are the common drug interactions of Enablex and Losartan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Coronary arterial stent insertion
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Injection site swelling

30-39:

Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Pneumonia
Sinusitis (inflammation of sinus)

40-49:

n/a

50-59:

Anaemia (lack of blood)
Balance disorder
Fall
Gastric disorder (disease of stomach)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Injection site pain
Injection site reaction
Proteinuria (presence of protein in the urine)
Renal failure (kidney dysfunction)

60+:

Headache (pain in head)
Chronic kidney disease
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Dry eye (lack of adequate tears)
Gait disturbance
Memory impairment
Pain in extremity
Tremor (trembling or shaking movements in one or more parts of your body)
Asthenia (weakness)
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)

What are the existing conditions these people have? *

High Blood Cholesterol: 16 people, 19.05%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 15 people, 17.86%
Pain: 14 people, 16.67%
Type 2 Diabetes: 13 people, 15.48%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 15.48%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 9.52%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 8 people, 9.52%
Diabetes: 8 people, 9.52%
Depression: 7 people, 8.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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